An Uncommon Cause of Membranous Glomerulonephritis

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An Uncommon Cause of Membranous Glomerulonephritis Anjali A. Satoskar, MD, Paul Kovach, MD, Kevin O'Reilly, MD, Tibor Nadasdy, MD, PhD  American Journal of Kidney Diseases  Volume 55, Issue 2, Pages 386-390 (February 2010) DOI: 10.1053/j.ajkd.2009.06.015 Copyright © 2010 National Kidney Foundation, Inc. Terms and Conditions

Figure 1 Hematoxylin and eosin–stained paraffin-embedded section. The glomerulus looks unremarkable (original magnification ×400). American Journal of Kidney Diseases 2010 55, 386-390DOI: (10.1053/j.ajkd.2009.06.015) Copyright © 2010 National Kidney Foundation, Inc. Terms and Conditions

Figure 2 Staining pattern for immunoglobulin G (IgG) subtypes. (A) Direct immunofluorescence shows moderate granular staining for IgG1 along the glomerular capillary wall, (B) absent staining for IgG2, (C) mild granular staining for IgG3 along the glomerular capillary wall, and (D) absent staining for IgG4 (frozen section; original magnification ×400). American Journal of Kidney Diseases 2010 55, 386-390DOI: (10.1053/j.ajkd.2009.06.015) Copyright © 2010 National Kidney Foundation, Inc. Terms and Conditions

Figure 3 Electron micrograph shows scattered subepithelial electron-dense immune-type deposits, irregularly distributed (arrows) (uranyl acetate lead citrate staining; original magnification ×12,000). American Journal of Kidney Diseases 2010 55, 386-390DOI: (10.1053/j.ajkd.2009.06.015) Copyright © 2010 National Kidney Foundation, Inc. Terms and Conditions

Figure 4 Electron micrograph shows endothelial tubuloreticular inclusion (arrow) (uranyl acetate lead citrate staining; original magnification ×30,000). American Journal of Kidney Diseases 2010 55, 386-390DOI: (10.1053/j.ajkd.2009.06.015) Copyright © 2010 National Kidney Foundation, Inc. Terms and Conditions