Angela Nakauka-Ddamba, Christopher J. Lengner  Cell Stem Cell 

Slides:



Advertisements
Similar presentations
Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer Shaun K. Olsen, Christopher D. Lima Molecular Cell Volume 49, Issue 5, Pages.
Advertisements

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.
What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell
Origins of Metastatic Traits Sakari Vanharanta, Joan Massagué Cancer Cell Volume 24, Issue 4, Pages (October 2013) DOI: /j.ccr
Bone Marrow-Derived Cell Therapy Stimulates Endogenous Cardiomyocyte Progenitors and Promotes Cardiac Repair Francesco S. Loffredo, Matthew L. Steinhauser,
Distribution of Human Embryonic Stem Cell Lines: Who, When, and Where Jennifer B. McCormick, Jason Owen-Smith, Christopher Thomas Scott Cell Stem Cell.
ER-to-Plasma Membrane Tethering Proteins Regulate Cell Signaling and ER Morphology Andrew G. Manford, Christopher J. Stefan, Helen L. Yuan, Jason A. MacGurn,
Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem
Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells David J. Wong, Helen Liu, Todd W. Ridky, David Cassarino, Eran Segal, Howard.
IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.
Fate Restriction and Multipotency in Retinal Stem Cells Lázaro Centanin, Burkhard Hoeckendorf, Joachim Wittbrodt Cell Stem Cell Volume 9, Issue 6, Pages.
Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells Keriayn N. Smith, Amar M. Singh, Stephen Dalton Cell Stem Cell Volume 7, Issue.
Normal and Leukemic Stem Cell Niches: Insights and Therapeutic Opportunities Koen Schepers, Timothy B. Campbell, Emmanuelle Passegué Cell Stem Cell Volume.
Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel
Quantitative Single-Cell Approaches to Stem Cell Research Martin Etzrodt, Max Endele, Timm Schroeder Cell Stem Cell Volume 15, Issue 5, Pages (November.
Illuminating the Properties of Prostate Luminal Progenitors
Stress Can Be a Good Thing for Blood Formation
Cancer: Inappropriate Expression of Stem Cell Programs?
Ras Brakes for Hippo Developmental Cell
Back to 2D Culture for Ground State of Intestinal Stem Cells
Martin Wahlestedt, David Bryder  Cell Stem Cell 
Stressed out? Healing Tips for Newly Reprogrammed Neurons
Volume 1, Issue 1, Pages (June 2007)
Responding to R-Spondin: Slit2 Potentiates Intestinal Regeneration
Responding to R-Spondin: Slit2 Potentiates Intestinal Regeneration
Cystic Fibrosis Patients Benefit from Mini Guts
The LUNGe to Model Alveolar Lung Diseases in a Dish
Why Myc? An Unexpected Ingredient in the Stem Cell Cocktail
In Search of Human Hematopoietic Stem Cell Identity
A Path to Insulin Independence: “The End of the Beginning”
Volume 9, Issue 2, Pages (August 2011)
Tamir Rashid, Toshihiro Kobayashi, Hiromitsu Nakauchi  Cell Stem Cell 
Anselme Perrier, Marc Peschanski  Cell Stem Cell 
Transplantable Liver Organoids Made from Only Three Ingredients
Justin Brumbaugh, Konrad Hochedlinger  Cell Stem Cell 
Organizing Organoids: Stem Cells Branch Out
Human Somatic Cell Nuclear Transfer Is Alive and Well
Stem Cell Therapies in Clinical Trials: Progress and Challenges
Stem Cell Aging and Sex: Are We Missing Something?
Why Myc? An Unexpected Ingredient in the Stem Cell Cocktail
Organoid Center Strategies for Accelerating Clinical Translation
Recreating Pluripotency?
Cerebral Organoids in a Dish: Progress and Prospects
Putting Two Heads Together to Build a Better Brain
Cystic Fibrosis Patients Benefit from Mini Guts
Not So Lonely at the Top for Cancer Stem Cells
Volume 21, Issue 1, Pages (July 2011)
Targeting β-catenin in CML: Leukemia Stem Cells Beware!
Order from Chaos: Single Cell Reprogramming in Two Phases
Transplantable Liver Organoids Made from Only Three Ingredients
MicroRNAs and Viral Infection
Meddling with METTLs in Normal and Leukemia Stem Cells
Sweet Relief: Reprogramming Gastric Endocrine Cells to Make Insulin
Illuminating the Black Box of Reprogramming
Powering Reprogramming with Vitamin C
NO Signals from the Cancer Stem Cell Niche
Sofia Gkountela, Amander T. Clark  Cell Stem Cell 
Anna B. Osipovich, Mark A. Magnuson  Cell Stem Cell 
Waddington’s Valleys and Captain Cook’s Islands
Volume 22, Issue 4, Pages (April 2018)
Chapter 29 - Stem Cells and Generation of New Cells in the
Volume 163, Issue 2, (October 2015)
Using Notches to Track Mammary Epithelial Cell Homeostasis
Mesp1 at the Heart of Mesoderm Lineage Specification
In Search of Human Hematopoietic Stem Cell Identity
Getting to the Core of Repeat Expansions by Cell Reprogramming
Moving Toward the Ground State
Ras Brakes for Hippo Developmental Cell
Knocking the Wnt out of the Sails of Leukemia Stem Cell Development
Justin Brumbaugh, Konrad Hochedlinger  Cell Stem Cell 
Presentation transcript:

Gut with the Program: Direct Reprogramming toward Intestinal Epithelium Realized  Angela Nakauka-Ddamba, Christopher J. Lengner  Cell Stem Cell  Volume 21, Issue 4, Pages 417-418 (October 2017) DOI: 10.1016/j.stem.2017.09.011 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 Properties of Primary and Reprogrammed Intestinal Organoids Reprogrammed organoids can be generated with combinations of three or four transcription factors and share some properties with their primary fetal counterparts; however, how well properties such as morphology, Lgr5+ cell presence, and Wnt pathway dependence reflect specific developmental stages in reprogrammed organoids remains unclear. Cell Stem Cell 2017 21, 417-418DOI: (10.1016/j.stem.2017.09.011) Copyright © 2017 Elsevier Inc. Terms and Conditions