Dodecyltrimethylammonium bromide (DTAB)

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Presentation transcript:

Dodecyltrimethylammonium bromide (DTAB)

(Infant respiratory distress syndrome (IRDS It is a syndrome in premature infants caused by developmental insufficiency of pulmonary surfactant production and structural immaturity in the lungs. It can also be a consequence of neonatal infection. It can also result from a genetic problem with the production of surfactant associated proteins. IRDS affects about 1% of newborn infants and is the leading cause of death in preterm infants. The syndrome is more frequent in males, Caucasians, infants of diabetic mothers, and the second born of premature twins.

What is alpha-1-antitrypsin deficiency? Alpha-1-antitrypsin deficiency (AATD) is a rare, inherited condition, which can cause lung and liver problems. It’s thought that about 25,000 people in the UK have the genetic condition though most remain healthy so few have been diagnosed.

COPD As a group of diseases is one of the leading causes of death in the United States. Unlike heart disease and other more common causes of death, the death rate for COPD appears to be rising.

What Causes Emphysema? The importance of cigarette smoking as a risk factor for developing emphysema cannot be overemphasized. Cigarette smoke contributes to this disease process in two ways. It destroys lung tissue, which results in the obstruction of air flow, and It causes inflammation and irritation of airways that can add to air flow obstruction.

Cystic fibrosis has an autosomal recessive pattern of inheritance

The CFTR protein is a channel protein that controls the flow of H2O and Cl- ions in and out of cells inside the lungs. When the CFTR protein is working correctly, ions freely flow in and out of the cells. However, when the CFTR protein is malfunctioning, these ions cannot flow out of the cell due to a blocked channel. This causes cystic fibrosis, characterized by the buildup of thick mucus in the lungs.

Health problems associated with cystic fibrosis