Clinical Utility of a Precision Medicine Test Evaluating Outpatients with Suspected Obstructive Coronary Artery Disease  Joseph A. Ladapo, MD, PhD, Matt.

Slides:



Advertisements
Similar presentations
High-dose Intravenous Immunoglobulin Therapy for Systemic Capillary Leak Syndrome (Clarkson Disease) Zhihui Xie, PhD, Eunice C. Chan, PhD, Lauren M. Long,
Advertisements

Low-Dose Aspirin in Patients with Stable Cardiovascular Disease: A Meta-analysis Jeffrey S. Berger, MD, MS, David L. Brown, MD, Richard C. Becker, MD The.
The utility of cardiac CT beyond the assessment of suspected coronary artery disease N. Kakouros, J. Giles, N.B. Crundwell, E.T.M. McWilliams Clinical.
Low-dose aspirin increases aspirin resistance in patients with coronary artery disease  Pui-Yin Lee, MBBS, Wai-Hong Chen, MBBS, William Ng, MBBS, Xi Cheng,
The Epidemic of the 20th Century: Coronary Heart Disease
Severe Tuberculosis Sepsis in an Immunocompetent Patient
Amay Parikh, MD, MBA, MS, Kunal Gupta, MD, MBA, Alan C
Sexuality The American Journal of Medicine
An Unusual Cause of Leg Ulcerations
Telemedicine Specialty Support Promotes Hepatitis C Treatment by Primary Care Providers in the Department of Veterans Affairs  Lauren A. Beste, MD, MSc,
Impact of More Restrictive Blood Transfusion Strategies on Clinical Outcomes: A Meta- analysis and Systematic Review  Shelley R. Salpeter, MD, Jacob S.
‘Chest Pain Typicality’ in Suspected Acute Coronary Syndromes and the Impact of Clinical Experience  Edward W. Carlton, MBChB, Martin Than, MBBS, Louise.
Comparative Effectiveness Research and Medical Informatics
Jeffrey H. Barsuk, MD, MS, Elaine R
Scientific and Organizational Collaboration in Comparative Effectiveness Research: The VA Cooperative Studies Program Model  Grant D. Huang, MPH, PhD,
Systematic Review of Guidelines on Peripheral Artery Disease Screening
David R. Curran, MD, Terence K
Telemedicine Specialty Support Promotes Hepatitis C Treatment by Primary Care Providers in the Department of Veterans Affairs  Lauren A. Beste, MD, MSc,
Sudden Cardiac Death, Mitral Valve Prolapse, and Long QT Syndrome
Systematic Review of the Mediterranean Diet for Long-Term Weight Loss
Jason Thomas, MD, Erica Saenz, MD, Paul Haggerty, MD 
Wandering Acute Myocardial Infarction
Overview of Current Learning Theories for Medical Educators
Todd A. Lee, PharmD, PhD, Brian Bartle, MPH, Kevin B. Weiss, MD, MPH 
Multimorbidity in Middle-Aged Adults with Cerebral Palsy
The Value of Percutaneous Coronary Intervention in Aortic Valve Stenosis with Coronary Artery Disease  Ronny Alcalai, MD, Nicola Viola, MD, Morris Mosseri,
Pseudotumor Cerebri: Early Manifestation of Adult Lyme Disease
Kaiser Permanente Creatinine Safety Program: A Mechanism to Ensure Widespread Detection and Care for Chronic Kidney Disease  John J. Sim, MD, Mark P.
Low-dose aspirin increases aspirin resistance in patients with coronary artery disease  Pui-Yin Lee, MBBS, Wai-Hong Chen, MBBS, William Ng, MBBS, Xi Cheng,
Lisa H. Williams, MD, MS, Carolyn M. Rutter, PhD, Wayne J
The Epidemic of the 20th Century: Coronary Heart Disease
Carotid Sinus Massage in Patients with Suspected Acute Myocardial Infarction, Tachycardia, and Left Bundle Branch Block  Teddy Weiss, MD, Yair Elitzur,
Symptomatic, Obstructive Cardiac Metastasis Can Respond to Chemotherapy  Matthew Cove, MD, Ruth Johnston, MD, Richard Cowan, MD, Philip Haji-Michael, MD 
Tick Tock The American Journal of Medicine
Medical professionalism and the generation gap
Thomas Rutledge, PhD, ABPP, Tanya S. Kenkre, PhD, MPH, Diane V
The Reply The American Journal of Medicine
Jessica L. Lee, MD, MS, Esther S. Oh, MD, Rebecca W. Lee, MD, Thomas E
TIA for the Internist The American Journal of Medicine
Metabolic Syndrome and Sexual Function in Postmenopausal Women
Cardiac Rehabilitation for Women across the Lifespan
Same-day cancellation of cardiac surgery: A retrospective review at a large academic tertiary referral center  Mark M. Smith, MD, William J. Mauermann,
The Impact of Prior Heart Failure Hospitalizations on Long-term Mortality Differs by Baseline Risk of Death  Naga V.A. Kommuri, MD, Todd M. Koelling,
Michael Mack, MD, David Taggart, MD 
The Reply The American Journal of Medicine
Does Methylphenidate Reduce the Symptoms of Chronic Fatigue Syndrome?
Sarah C. Snow, MD, Gregg C. Fonarow, MD, Joseph A
Joseph A. Dearani, MD, Michael J. Ackerman, MD, PhD 
Chronic obstructive pulmonary disease severity influences outcomes after off-pump coronary artery bypass  Benjamin Medalion, MD, Michael G. Katz, MD,
To Reduce Stroke with PFO Closure, Respect the Shunt
Distal Embolization of Thrombus in Acute Myocardial Infarction
Modified Thrombolytic Therapy for Massive Pulmonary Emboli
Alternative Trends Estimate and Stakeout Synthetic Marijuana Use
National Trends in Ambulatory Oral Anticoagulant Use
A Review of Learner Impact on Faculty Productivity
Sister Mary Joseph's Node
Calcification of the Coronary Artery
Jeffrey H. Barsuk, MD, MS, Elaine R
Primary Care Management of Skin Abscesses Guided by Ultrasound
David E. Winchester, MD, David C. Wymer, MD, Roger Y
The future of cardiac surgery training: A survival guide
The Association Between Barium Examination and Subsequent Appendicitis: A Nationwide Population-Based Study  Hao-Ming Li, MD, Lee-Ren Yeh, MD, Ying-Kai.
Direct Observation of Residents: A Model for an Assessment System
Grace C. Huang, MD, C. Christopher Smith, MD, Craig E
Clinical effectiveness of laparoscopic fundoplication in a U. S
Falls in Older Adults: Risk Assessment, Management and Prevention
Emily G. McDonald, MD, MSc, Ramy R. Saleh, MD, Todd C. Lee, MD, MPH 
Daniel E. Weiner, MD, MS, Hocine Tighiouart, MS, John L
David Tian, MD, Ram Jhingan Mohan, MD, Gary Stallings, MD 
Hypophosphatemia: Diagnostic Significance in Legionnaires’ Disease
Presentation transcript:

Clinical Utility of a Precision Medicine Test Evaluating Outpatients with Suspected Obstructive Coronary Artery Disease  Joseph A. Ladapo, MD, PhD, Matt Budoff, MD, David Sharp, DO, Michael Zapien, MS, Lin Huang, PhD, Bruce Maniet, DO, Lee Herman, MD, Mark Monane, MD, MS  The American Journal of Medicine  Volume 130, Issue 4, Pages 482.e11-482.e17 (April 2017) DOI: 10.1016/j.amjmed.2016.11.021 Copyright © 2016 The Authors Terms and Conditions

Figure 1 Study design/patient flow. ASGES = age/sex/gene expression score; CAD = coronary artery disease. The American Journal of Medicine 2017 130, 482.e11-482.e17DOI: (10.1016/j.amjmed.2016.11.021) Copyright © 2016 The Authors Terms and Conditions

Figure 2 Relationship between age/sex/gene expression score (ASGES) grouped in sets of 5 score units and percentage of referral to Cardiology or further cardiac testing. The American Journal of Medicine 2017 130, 482.e11-482.e17DOI: (10.1016/j.amjmed.2016.11.021) Copyright © 2016 The Authors Terms and Conditions