Protein Targeting: ER Leads the Way to the Inner Nuclear Envelope

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Protein Targeting: ER Leads the Way to the Inner Nuclear Envelope Craig Blackstone  Current Biology  Volume 27, Issue 23, Pages R1284-R1286 (December 2017) DOI: 10.1016/j.cub.2017.10.037 Copyright © 2017 Terms and Conditions

Figure 1 ER and nuclear envelope organization. Schematic diagram showing the continuity and different morphologies of the ER. Atlastin GTPases mediate homotypic fusion of ER tubules to create three-way junctions, and ER-shaping proteins such as reticulons generate high curvature (enlargements shown). Abbreviations: INM, inner nuclear membrane; LINC, linker of nucleoskeleton and cytoskeleton; NPC, nuclear pore complex; ONM, outer nuclear membrane. (Image drawn by Alan Hoofring.) Current Biology 2017 27, R1284-R1286DOI: (10.1016/j.cub.2017.10.037) Copyright © 2017 Terms and Conditions