Transvection Current Biology

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Presentation transcript:

Transvection Current Biology Takashi Fukaya, Michael Levine  Current Biology  Volume 27, Issue 19, Pages R1047-R1049 (October 2017) DOI: 10.1016/j.cub.2017.08.001 Copyright © 2017 Elsevier Ltd Terms and Conditions

Figure 1 Transvection in Drosophila. (A) Transvection in bx34e/Ubx1 trans-heterozygotes. Intronic abx and BRE enhancers on the Ubx1allele activate transcription from the bx34e allele in trans. (B) Loss of cis-linked promoter augments transvection. UbxMx6 mutation consists of a 3.4 kb deletion including the Ubx promoter. (C) 5´ wing and body enhancers on the promoter-less allele activate transcription from the enhancer-less allele in trans. W, wing enhancer; B, body enhancer; Br, bristle enhancer; T, tarsal claw enhancer. (D) Insulator DNAs facilitate transvection at yellow. Current Biology 2017 27, R1047-R1049DOI: (10.1016/j.cub.2017.08.001) Copyright © 2017 Elsevier Ltd Terms and Conditions