Roh Yanagida, MD, PhD, Lawrence S. C. Czer, MD, Nancy L

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Presentation transcript:

Impact of Virtual Cross Match on Waiting Times for Heart Transplantation Roh Yanagida, MD, PhD, Lawrence S.C. Czer, MD, Nancy L. Reinsmoen, PhD, Kai Cao, MD, Matthew Rafiei, BS, Michele A. De Robertis, RN, James Mirocha, MS, Robert M. Kass, MD, Jon A. Kobashigawa, MD, Alfredo Trento, MD The Annals of Thoracic Surgery Volume 92, Issue 6, Pages 2104-2111 (December 2011) DOI: 10.1016/j.athoracsur.2011.07.082 Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Waiting time for patients before (A) and after (B) VC. No patients waited longer than a year after VC. (PRA = panel reactive antibody; preVC = prospective cross match; VC = virtual cross match.) The Annals of Thoracic Surgery 2011 92, 2104-2111DOI: (10.1016/j.athoracsur.2011.07.082) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Kaplan-Meier estimates of survival for sensitized and nonsensitized patients before and after VC. (PRA = panel reactive antibody; preVC = prospective cross match; VC = virtual cross match.) The Annals of Thoracic Surgery 2011 92, 2104-2111DOI: (10.1016/j.athoracsur.2011.07.082) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Kaplan-Meier estimates of survival by sensitized status. (PRA = panel reactive antibody.) The Annals of Thoracic Surgery 2011 92, 2104-2111DOI: (10.1016/j.athoracsur.2011.07.082) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Kaplan-Meier estimates of survival before and after VC. (preVC = prospective cross match; VC = virtual cross match.) The Annals of Thoracic Surgery 2011 92, 2104-2111DOI: (10.1016/j.athoracsur.2011.07.082) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Kaplan-Meier estimates of freedom from 3A (2R) cellular rejection for sensitized and nonsensitized patients before and after virtual cross match. (PRA = panel reactive antibody; preVC = prospective cross match; VC = virtual cross match.) The Annals of Thoracic Surgery 2011 92, 2104-2111DOI: (10.1016/j.athoracsur.2011.07.082) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 Kaplan-Meier estimates of freedom from antibody-mediated rejection for sensitized and nonsensitized patients before and after virtual cross match. (PRA = panel reactive antibody; preVC = prospective cross match; VC = virtual cross match.) The Annals of Thoracic Surgery 2011 92, 2104-2111DOI: (10.1016/j.athoracsur.2011.07.082) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 7 Donor geographic area outside regional organ procurement organization (OPO) (OneLegacy). Relative size of the dot depicts the number of donors from each site. Shaded area corresponds to the area covered by the regional OPO. (preVC = prospective cross match; VC = virtual cross match.) The Annals of Thoracic Surgery 2011 92, 2104-2111DOI: (10.1016/j.athoracsur.2011.07.082) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions