Experience with lung transplantation

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Presentation transcript:

Experience with lung transplantation Axel Haverich, MD The Annals of Thoracic Surgery Volume 67, Issue 2, Pages 305-312 (February 1999) DOI: 10.1016/S0003-4975(99)00021-1

Fig 1 Thoracic organ transplantation program at Hannover Medical School depicting the annual number of operations for heart–lung transplantation (HLTx), single-lung transplantation (SLTx), bilateral lung transplantation (DLTx), and heart transplantation (HTx). The Annals of Thoracic Surgery 1999 67, 305-312DOI: (10.1016/S0003-4975(99)00021-1)

Fig 2 Algorithm of treatment modalities in acute pulmonary failure, potentially resulting in lung transplantation (LTx). (NO = nitric oxide; C1EI = C1 esterase inhibitor; ECMO = extracorporeal membrane oxygenation; uni = unilateral.) The Annals of Thoracic Surgery 1999 67, 305-312DOI: (10.1016/S0003-4975(99)00021-1)

Fig 3 Actuarial survival in subgroups after (A) lung transplantation, (B) preoperative mechanical ventilation, and (C) pretransplantation extracorporeal membrane oxygenation (ECMO). (D) Comparison between pretransplantation cytomegalovirus (CMV) serology of recipients. (n.s. = not significant; ReTx = repeat transplantation; Tx = transplantation; + = positive; − = negative.) The Annals of Thoracic Surgery 1999 67, 305-312DOI: (10.1016/S0003-4975(99)00021-1)

Fig 4 Criteria for organ donors required for lung transplantation: comparison between 1988 and 1998. (FiO2 = inspired oxygen fraction.) The Annals of Thoracic Surgery 1999 67, 305-312DOI: (10.1016/S0003-4975(99)00021-1)

Fig 5 Annual number of lung transplantations at Hannover Medical School between January 1987 and October 1998. (Abbreviations are as in Fig 1.). The Annals of Thoracic Surgery 1999 67, 305-312DOI: (10.1016/S0003-4975(99)00021-1)

Fig 6 Indications for lung transplantation. (A) Registry data from the International Society for Heart and Lung Transplantation (ISHLT). (B) Data from Hannover Medical School (B/DLTx = bilateral lung transplantation; CF = cystic fibrosis; IPF = idiopathic pulmonary fibrosis; misc. = miscellaneous; PHT = pulmonary hypertension; other abbreviations are as in Fig 1.) The Annals of Thoracic Surgery 1999 67, 305-312DOI: (10.1016/S0003-4975(99)00021-1)

Fig 7 Actuarial survival after lung transplantation (Tx) (Hannover) for (A) the entire population, (B) subgroups according to type of transplantation, (C) subgroups according to underlying disease, and (D) results during 1988 through 1993 compared with 1994 through 1998. (Pulm. = pulmonary; other abbreviations as in Figs 1 and 6.) The Annals of Thoracic Surgery 1999 67, 305-312DOI: (10.1016/S0003-4975(99)00021-1)