Survival after the Diagnosis of Hyperparathyroidism: A Population-based Study1 Robert A Wermers, Sundeep Khosla, Elizabeth J Atkinson, Clive S Grant,

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Survival after the Diagnosis of Hyperparathyroidism: A Population-based Study1 Robert A Wermers, Sundeep Khosla, Elizabeth J Atkinson, Clive S Grant, Stephen F Hodgson, W.Michael O’Fallon, L.Joseph Melton The American Journal of Medicine Volume 104, Issue 2, Pages 115-122 (February 1998) DOI: 10.1016/S0002-9343(97)00270-2

Fig. 1 Cumulative incidence of parathyroid surgery among Rochester, Minnesota residents with definite primary hyperparathyroidism recognized in the prescreening era (1965 to June 1974) versus the postscreening era (July 1974 to 1992) (P = 0.11 for difference between the two curves). The American Journal of Medicine 1998 104, 115-122DOI: (10.1016/S0002-9343(97)00270-2)

Fig. 2 Top panel: survival among Rochester, Minnesota residents with primary hyperparathyroidism in the prescreening era (1965 to June 1974) compared with that expected for Minnesota white residents of similar age and gender (P = 0.71 for difference between observed versus expected survival). Bottom panel: survival among Rochester, Minnesota residents with primary hyperparathyroidism in the postscreening era (July 1974 to 1992) compared with that expected for Minnesota white residents of similar age and gender (P <0.02 for difference between observed versus expected survival). The American Journal of Medicine 1998 104, 115-122DOI: (10.1016/S0002-9343(97)00270-2)

Fig. 3 Survival as a function of quartile of serum calcium levels (I = 10.2 to 10.5 mg/dL; II = 10.6 to 10.7 mg/dL; III = 10.8 to 11.1 mg/dL; and IV = 11.2 to 16.0 mg/dL) among Rochester, Minnesota residents with primary hyperparathyroidism. Group IV had significantly reduced survival (P <0.001) compared with the other 3 groups. The American Journal of Medicine 1998 104, 115-122DOI: (10.1016/S0002-9343(97)00270-2)

Fig. 4 Survival among Rochester, Minnesota residents with definite primary hyperparathyroidism in the highest serum calcium level quartile (11.2 to 16.0 mg/dL) compared with that expected for Minnesota white residents of similar age and gender before parathyroid surgery (A) and following parathyroid surgery (B) (P = 0.91 and 0.41, respectively for difference between observed versus expected survivals). The American Journal of Medicine 1998 104, 115-122DOI: (10.1016/S0002-9343(97)00270-2)