Assessment of statin therapy, LDL-C levels, and cardiovascular events among high-risk patients in the United States Sudhir K. Unni, PhD, MBA, Ruben G.W.

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Assessment of statin therapy, LDL-C levels, and cardiovascular events among high-risk patients in the United States Sudhir K. Unni, PhD, MBA, Ruben G.W. Quek, PhD, Joseph Biskupiak, PhD, MBA, Vinson C. Lee, PharmD, MS, FCPhA, Xiangyang Ye, MS, Shravanthi R. Gandra, PhD, MBA Journal of Clinical Lipidology Volume 10, Issue 1, Pages 63-71.e3 (January 2016) DOI: 10.1016/j.jacl.2015.09.008 Copyright © 2016 National Lipid Association Terms and Conditions

Figure 1 Patient selection flowchart. CHD, coronary heart disease; CHD RE, coronary heart disease risk equivalent; CKD, chronic kidney disease; CV, cardiovascular. Journal of Clinical Lipidology 2016 10, 63-71.e3DOI: (10.1016/j.jacl.2015.09.008) Copyright © 2016 National Lipid Association Terms and Conditions

Figure 2 Statin therapy patterns. CHD, coronary heart disease; CHD RE, coronary heart disease risk equivalent; CV, cardiovascular. Journal of Clinical Lipidology 2016 10, 63-71.e3DOI: (10.1016/j.jacl.2015.09.008) Copyright © 2016 National Lipid Association Terms and Conditions

Figure 3 Proportion of patients with low-density lipoprotein cholesterol ≥ 100 mg/dL pre- and post-index date in the 3 cohorts. CHD, coronary heart disease; CHD RE, coronary heart disease risk equivalent; CV, cardiovascular; LDL-C, low-density lipoprotein cholesterol. Journal of Clinical Lipidology 2016 10, 63-71.e3DOI: (10.1016/j.jacl.2015.09.008) Copyright © 2016 National Lipid Association Terms and Conditions

Figure 4 Cumulative incidence rate of post-index CV events for CHD and CHD RE cohorts. CABG, coronary artery bypass graft; CHD, coronary heart disease; CHD RE, coronary heart disease risk equivalent; CV, cardiovascular; PCI, percutaneous coronary intervention. Journal of Clinical Lipidology 2016 10, 63-71.e3DOI: (10.1016/j.jacl.2015.09.008) Copyright © 2016 National Lipid Association Terms and Conditions