Genital β2-Microglobulin Amyloidoma in a Long-Term Dialysis Patient

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Genital β2-Microglobulin Amyloidoma in a Long-Term Dialysis Patient Itsuko Okuda, MD, Yoshifumi Ubara, MD, Kenmei Takaichi, MD, Izubu Kitajima, MD, Noriko Motoi, MD, Shigeo Hara, MD, Takashi Kokubo, MD  American Journal of Kidney Diseases  Volume 48, Issue 3, Pages e35-e39 (September 2006) DOI: 10.1053/j.ajkd.2006.05.009 Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 1 Axial CT scan shows a large mass (arrow) on the back of the pubic bone. The mass is of soft-tissue density and is accompanied by diffuse calcification. American Journal of Kidney Diseases 2006 48, e35-e39DOI: (10.1053/j.ajkd.2006.05.009) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 2 Sagittal MRI shows a mass measuring 9.0 × 6.0 × 5.0 cm located between the vagina and rectum. (A) A T2-weighted image shows the mass hypointense (arrow) compared with adjacent muscle. (B) A T1-weighted image shows the mass isointense (arrow) to muscle. (C) A contrast-enhanced T1-weighted magnetic resonance image (arrow). American Journal of Kidney Diseases 2006 48, e35-e39DOI: (10.1053/j.ajkd.2006.05.009) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 3 (A) Hematoxylin and eosin stain of the mass shows deposition of an amorphous eosinophilic material (arrow) in the interstitium of the vaginal tissue. (B) The material is positive for Congo red stain (arrow). (C) By immunohistochemical staining, the amyloid material is positive for β2MG (arrow). (Original magnification: [A, B] ×4; [C] ×20.) American Journal of Kidney Diseases 2006 48, e35-e39DOI: (10.1053/j.ajkd.2006.05.009) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions