Fundic Gland Polyp Dysplasia Is Common in Familial Adenomatous Polyposis Laura K. Bianchi, Carol A. Burke, Ana E. Bennett, Rocio Lopez, Hennie Hasson, James M. Church Clinical Gastroenterology and Hepatology Volume 6, Issue 2, Pages 180-185 (February 2008) DOI: 10.1016/j.cgh.2007.11.018 Copyright © 2008 AGA Institute Terms and Conditions
Figure 1 Histopathologic appearance of dysplasia in FGPs. (A) LGD: 4 glands in the upper right-hand corner show nuclear stratification, elongation, and hyperchromasia extending from the bottom of foveolar pits onto the surface epithelium. The lower dilated fundic glands confirm the classification of FGP for this lesion. (B) HGD: marked glandular complexity and back-to-back glands with scant intervening stroma. The nuclei are enlarged, hyperchromatic, and there is full-thickness epithelial stratification with loss of nuclear polarity (magnification, 100×). Clinical Gastroenterology and Hepatology 2008 6, 180-185DOI: (10.1016/j.cgh.2007.11.018) Copyright © 2008 AGA Institute Terms and Conditions