Interleukin-2 as a marker for detecting asymptomatic individuals in areas where Leishmania infantum is endemic A.V. Ibarra-Meneses, E. Carrillo, C. Sánchez,

Slides:

Advertisements

Similar presentations

Volume 66, Issue 6, Pages (June 2013)

Advertisements

Interleukin-2 as a marker for detecting asymptomatic individuals in areas where Leishmania infantum is endemic A.V. Ibarra-Meneses, E. Carrillo, C. Sánchez,

Protease inhibitor monotherapy is effective in controlling human immunodeficiency virus 1 shedding in the male genital tract A. Torres-Cornejo, O.J.

Circulating levels of sTNFR and discrepancy between cytotoxicity and immunoreactivity of TNF-α in patients with visceral leishmaniasis I.M. Medeiros,

Helicobacter pylori resistance to antibiotics in 2014 in France detected by phenotypic and genotypic methods A. Ducournau, L. Bénéjat, E. Sifré, E. Bessède,

KLIC-score for predicting early failure in prosthetic joint infections treated with debridement, implant retention and antibiotics E. Tornero, L. Morata,

Detection of fungal DNA in lysis–centrifugation blood culture for the diagnosis of invasive candidiasis in neonatal patients L. Trovato, P. Betta, M.G.

Cerebrospinal fluid cytokines in enterovirus 71 brain stem encephalitis and echovirus meningitis infections of varying severity S.-M. Wang, H.-Y. Lei,

I.J. Schalk Clinical Microbiology and Infection

D. Khalil, M. Hultin, M.U. Rashid, B. Lund

Evaluation of tumor necrosis factor-α, interleukin-6 and C-reactive protein plasma levels as predictors of bacteremia in patients presenting signs of.

C.-P. Kuo, C.-L. Wu, H.-T. Ho, C.G. Chen, S.-I. Liu, Y.-T. Lu

Risk factors for cryptococcal infection among patients with rheumatoid arthritis receiving different immunosuppressive medications T.-L. Liao, Y.-M.

Migrant health—a cause for concern?

Aetiology of diarrhoeal disease and evaluation of viral–bacterial coinfection in children under 5 years old in China: a matched case–control study L.L.

Diagnostic Performance of a Cytokine and IFN-γ–Induced Chemokine mRNA Assay after Mycobacterium tuberculosis–Specific Antigen Stimulation in Whole Blood.

Genetic influence on cytokine production in meningococcal disease

Y. Higashimoto, M. Ohata, Y. Yamagata, T. Iwata, M. Masuda, T

Screening of migrants for tuberculosis identifies patients with multidrug-resistant tuberculosis but is not sufficient P. Helbling Clinical Microbiology.

Rickettsia conorii is a potent complement activator in vivo and combined inhibition of complement and CD14 is required for attenuation of the cytokine.

M. Giannella, B. Pinilla, J. A. Capdevila, J. Martínez Alarcón, P

R. Cantón Clinical Microbiology and Infection

A. F. Simonetti, C. Garcia-Vidal, D. Viasus, D. García-Somoza, J

Volume 54, Issue 4, Pages (October 1998)

Individuals with inherited chromosomally integrated human herpes virus 6 (ciHHV-6) have functionally active HHV-6 specific T-cell immunity V. Strenger,

Genetic influence on cytokine production in meningococcal disease

V.E. Nambudiri, R.C. Dwyer, C.A. Camargo, T.S. Kupper, D.J. Pallin

Increased incidence of nitroimidazole-refractory giardiasis at the Hospital for Tropical Diseases, London: 2008–2013 L.E.B. Nabarro, R.A. Lever, M. Armstrong,

Epidemiology, risk factors and impact on long-term pancreatic function of infection following pancreas-kidney transplantation J.M. Herrero-Martínez,

S. Skovbjerg, K. Roos, F. Nowrouzian, M. Lindh, S. E. Holm, I

Evaluation of Th1/Th2 cytokines as a rapid diagnostic tool for severe infection in paediatric haematology/oncology patients by the use of cytometric bead.

Trends in length of stay, mortality and readmission among patients with community- acquired bacteraemia M. Søgaard, R.W. Thomsen, R.B. Bang, H.C. Schønheyder,

First isolation of Akkermansia muciniphila in a blood-culture sample

Effect of moxifloxacin on secretion of cytokines by human monocytes stimulated with lipopolysaccharide F.G. Araujo, T.L. Slifer, J.S. Remington Clinical.

M. De Fost, W. Chierakul, R. Limpaiboon, A. Dondorp, N. J. White, T

A dynamic relationship between mucosal T helper type 17 and regulatory T-cell populations in nasopharynx evolves with age and associates with the clearance.

M. Sabria, J. Alvarez, A. Dominguez, A. Pedrol, G. Sauca, L

Comparison of respiratory virus shedding by conventional and molecular testing methods in patients with haematological malignancy L. Richardson, J. Brite,

Clinical Microbiology and Infection

C. Garcia-Vidal, I. Sanchez-Rodriguez, A. F. Simonetti, J. Burgos, D

L. Y. A. Chai, R. Naesens, A. L. Khoo, M. V. Abeele, K

Tumoral presence of human cytomegalovirus is associated with shorter disease-free survival in elderly patients with colorectal cancer and higher levels.

Enhanced surveillance of carbapenemase-producing Gram-negative bacteria to support national and international prevention and control efforts R. Freeman

T-cell responses against tuberculin and sensitin in children with tuberculosis and non- tuberculosis mycobacterial lymphadenopathy K. Magdorf, S.D. Schuck,

Epidemiology of opportunistic infections in AIDS patients

Hepatitis C virus and interferon type III (interferon-λ3/interleukin-28B and interferon-λ4): genetic basis of susceptibility to infection and response.

Detection of interleukin-2 in addition to interferon-γ discriminates active tuberculosis patients, latently infected individuals, and controls R. Biselli,

A. Pierangeli, F. Cannella, C. Scagnolari, M. Gentile, I. Sciandra, G

Y. -P. Ding, M. -F. Liang, J. -b. Ye, Q. -h. Liu, C. -h. Xiong, B

S. David, M. Mentasti, J. Parkhill, V.J. Chalker

Previously unknown species of Aspergillus

M. Korva, A. Saksida, N. Kejzar, C. Schmaljohn, T. Avŝiĉ-Zupanc

Systematic review of antibiotic consumption in acute care hospitals

Evidence for human immunodeficiency virus and Cryptococcus neoformans interactions in the pro-inflammatory and anti-inflammatory responses in blood during.

M. Daudin, P. Tattevin, B. Lelong, E. Flecher, S. Lavoué, C. Piau, A

Identification of risk factors associated with nosocomial infection by rotavirus P4G2, in a neonatal unit of a tertiary-care hospital R. Herruzo, F.

Relationship between the early Boceprevir-S isomer plasma concentrations and the onset of breakthrough during HCV genotype 1 triple therapy L. Boglione,

Presence of sandflies infected with Leishmania infantum and Massilia virus in the Marseille urban area† B. Faucher, R. Piarroux, C. Mary Clinical Microbiology.

Leishmaniasis in immunosuppressed individuals

Accuracy of an immune diagnostic assay based on RD1 selected epitopes for active tuberculosis in a clinical setting: a pilot study D. Goletti, S. Carrara,

M.T. Pérez-Rodríguez, A. Sousa, P. Martínez-Cueto, A. Ocampo

Shorter duration of antibiotic treatment for acute bacteraemic cholangitis with successful biliary drainage: a retrospective cohort study A. Doi, T.

V.A.C.M. Koeken, A.J. Verrall, M.G. Netea, P.C. Hill, R. van Crevel

Immunomodulation by Interleukin-10 Therapy Decreases the Incidence of Relapse and Prolongs the Relapse-free Interval in Psoriasis Markus Friedrich, Wolf-Dietrich.

J.L. Balcázar Clinical Microbiology and Infection

Impact of antibiotic restrictions: the patient's perspective

Sotirios Tsiodras, MD, MSc, ScD, George Samonis, MD, Dimitrios T

The burden of chikungunya in the Pacific

CMI readers' survey Clinical Microbiology and Infection

Rajko Saletinger, Mario Poljak, Franc Strle

Presentation transcript:

Interleukin-2 as a marker for detecting asymptomatic individuals in areas where Leishmania infantum is endemic A.V. Ibarra-Meneses, E. Carrillo, C. Sánchez, J. García-Martínez, D. López Lacomba, J.V. San Martin, F. Alves, J. Alvar, J. Moreno Clinical Microbiology and Infection Volume 22, Issue 8, Pages 739.e1-739.e4 (August 2016) DOI: 10.1016/j.cmi.2016.05.021 Copyright © 2016 The Author(s) Terms and Conditions

Fig. 1 Cytokine production in whole blood in response to soluble Leishmania antigen (SLA) stimulation for 24 h. (a–d) Production of (a) interferon-γ (IFN-γ), (b) tumour necrosis factor-α (TNF-α), (c) interleukin-10 (IL-10) and (d) IL-2 in plasma following 24 h of SLA stimulation of whole blood from patients with cured visceral leishmaniasis (VL) patients (CVL; n=18), asymptomatic participants (Asympt; n=47), patients with active disease (VL; n=18), and negative controls (NVL; n=50). Horizontal bars represent the mean concentration for each cytokine. Data were analysed using the Mann–Whitney U test. *p ≤0.05, **p ≤0.01, ***p ≤0.001, ****p ≤0.0001. (e,f) Receiver operating characteristic curve analysis to determine the sensitivity and specificity of IFN-γ and IL-2 to detect asymptomatic participants. Clinical Microbiology and Infection 2016 22, 739.e1-739.e4DOI: (10.1016/j.cmi.2016.05.021) Copyright © 2016 The Author(s) Terms and Conditions