Mark J. Russo, MD, MS, David I. Sternberg, MD, Kimberly N

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Presentation transcript:

Postlung Transplant Survival is Equivalent Regardless of Cytomegalovirus Match Status Mark J. Russo, MD, MS, David I. Sternberg, MD, Kimberly N. Hong, MHSA, Robert A. Sorabella, BA, Alan J. Moskowitz, MD, Annetine C. Gelijns, PhD, Jessie R. Wilt, MD, Frank D’Ovidio, MD, PhD, Steve M. Kawut, MD, MS, Selim M. Arcasoy, MD, Joshua R. Sonett, MD The Annals of Thoracic Surgery Volume 84, Issue 4, Pages 1129-1135 (October 2007) DOI: 10.1016/j.athoracsur.2007.05.037 Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Kaplan–Meier survival analysis after lung transplantation by cytomegalovirus (CMV) serologic status. (D+ = donor CMV+; Dx = donor CMV+ or −; R− = recipient CMV−; R+ = recipient CMV+.) The Annals of Thoracic Surgery 2007 84, 1129-1135DOI: (10.1016/j.athoracsur.2007.05.037) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Kaplan–Meier survival functions for posttransplant survival within each of the three eras stratified by cytomegalovirus (CMV) match status. (A) Group 2 (D+⊻R−); (B) group 2 (Dx⊻R+); (C) group 3 (D−⊻R−). 4-year incremental time periods for the 1991 to 2004 era. (D+ = donor CMV+; Dx = donor CMV+ or −; R− = recipient CMV−; R+ = recipient CMV+.) The Annals of Thoracic Surgery 2007 84, 1129-1135DOI: (10.1016/j.athoracsur.2007.05.037) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Kaplan–Meier survival functions for posttransplant bronchiolitis obliterans, infection, and rejection–free survival in the current era. (A) Bronchiolitis obliterans; (B) infection; (C) rejection. (D+ = donor cytomegalovirus +; Dx = donor cytomegalovirus + or −; R− = recipient cytomegalovirus −; R+ = recipient cytomegalovirus +.) The Annals of Thoracic Surgery 2007 84, 1129-1135DOI: (10.1016/j.athoracsur.2007.05.037) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Kaplan–Meier survival functions for posttransplant bronchiolitis obliterans stratified by cytomegalovirus (CMV) match status and CMV prophylaxis. (A) Group I (D+⊻R−); (B) group II (Dx⊻R+); (C) group III (D−⊻R−). (D+ = donor CMV+; Dx = donor CMV+ or −; R− = recipient CMV−; R+ = recipient CMV+.) The Annals of Thoracic Surgery 2007 84, 1129-1135DOI: (10.1016/j.athoracsur.2007.05.037) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions