Development of the Autosomal Dominant Polycystic Kidney Disease Impact Scale: A New Health-Related Quality-of-Life Instrument Dorothee Oberdhan, Jason.

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Presentation transcript:

Development of the Autosomal Dominant Polycystic Kidney Disease Impact Scale: A New Health-Related Quality-of-Life Instrument Dorothee Oberdhan, Jason C. Cole, Holly B. Krasa, Rebecca Cheng, Frank S. Czerwiec, Ron D. Hays, Arlene B. Chapman, Ronald D. Perrone American Journal of Kidney Diseases Volume 71, Issue 2, Pages 225-235 (February 2018) DOI: 10.1053/j.ajkd.2017.08.020 Copyright © 2017 The Authors Terms and Conditions

Figure 1 Development of the Autosomal Dominant Polycystic Kidney Disease Impact Scale (ADPKD-IS). Abbreviations: CKD, chronic kidney disease; PRO, patient-reported outcome. American Journal of Kidney Diseases 2018 71, 225-235DOI: (10.1053/j.ajkd.2017.08.020) Copyright © 2017 The Authors Terms and Conditions

Figure 2 Autosomal Dominant Polycystic Kidney Disease Impact Scale (ADPKD-IS) final conceptual framework and model. American Journal of Kidney Diseases 2018 71, 225-235DOI: (10.1053/j.ajkd.2017.08.020) Copyright © 2017 The Authors Terms and Conditions

Figure 3 Concept mapping between the 12-Item Short Form Health Survey version 2 (SF-12v2) and Autosomal Dominant Polycystic Kidney Disease Impact Scale (ADPKD-IS). American Journal of Kidney Diseases 2018 71, 225-235DOI: (10.1053/j.ajkd.2017.08.020) Copyright © 2017 The Authors Terms and Conditions

Figure 4 Autosomal Dominant Polycystic Kidney Disease Impact Scale (ADPKD-IS), EQ-5D, and 12-Item Short Form Health Survey (SF-12) mean at baseline by chronic kidney disease (CKD) stage. Abbreviations: MCS, Mental Component Summary; PCS, Physical Component Summary. American Journal of Kidney Diseases 2018 71, 225-235DOI: (10.1053/j.ajkd.2017.08.020) Copyright © 2017 The Authors Terms and Conditions

Figure 5 Percent difference compared to patients with chronic kidney disease stage 1 (CKD 1) at baseline. Abbreviations: ADPKD-IS, Autosomal Dominant Polycystic Kidney Disease Impact Scale; MCS, Mental Component Summary; PCS, Physical Component Summary; SF-12, 12-Item Short Form Health Survey. American Journal of Kidney Diseases 2018 71, 225-235DOI: (10.1053/j.ajkd.2017.08.020) Copyright © 2017 The Authors Terms and Conditions

Figure 6 Autosomal Dominant Polycystic Kidney Disease Impact Scale (ADPKD-IS), EQ-5D, and 12-Item Short Form Health Survey (SF-12) Cohen d effect size at baseline by chronic kidney disease (CKD) stage. Abbreviations: MCS, Mental Component Summary; PCS, Physical Component Summary. American Journal of Kidney Diseases 2018 71, 225-235DOI: (10.1053/j.ajkd.2017.08.020) Copyright © 2017 The Authors Terms and Conditions