Self-expanding transcatheter aortic valve replacement using alternative access sites in symptomatic patients with severe aortic stenosis deemed extreme.

Slides:

Advertisements

Similar presentations

ACC 2015 Jae K. Oh, MD On Behalf of the US CoreValve Investigators Remodeling of Self-Expanding Transcatheter Aortic Valve Is Responsible for Regression.

Advertisements

Outcomes in the CoreValve US High-Risk Pivotal Trial in Patients with a Society of Thoracic Surgeons Predicted Risk of Mortality Less than or Equal to.

TRANSFORM (Multicenter Experience With Rapid Deployment Edwards INTUITY Valve System for Aortic Valve Replacement) US clinical trial: Performance of a.

One-Year Outcomes of Transcatheter Aortic Valve Replacement in Patients With End- Stage Renal Disease Daniel P. O’Hair, MD, Tanvir K. Bajwa, MD, Stanley.

Transcatheter aortic valve replacement in patients with severe aortic stenosis who are at high risk for surgical complications: Summary assessment of.

Max B. Mitchell, MD The Journal of Thoracic and Cardiovascular Surgery

Of mice and men and surgical transcatheter aortic valve insertion

CoreValve Continued Access Study Shows Continued Improvement in 1-Year Outcomes With Self-Expanding Transcatheter Aortic Valve Replacement Steven J. Yakubov,

Aortic valve replacement in low-flow, low-gradient aortic stenosis: Left ventricular ejection fraction matters Victor Dayan, MD, PhD, Philippe Pibarot,

A contemporary analysis of pulmonary hypertension in patients undergoing mitral valve surgery: Is this a risk factor? Daniel H. Enter, MD, Anthony Zaki,

Robert J. Dabal, MD, James K

Aborted episode of sudden death due to delayed heart block after transcatheter aortic valve insertion Kevin L. Greason, MD, Paul A. Friedman, MD, Daniel.

Scott Goldman, MD, Anson Cheung, MD, Joseph E. Bavaria, MD, Michael R

David W. Barbara, MD, William J. Mauermann, MD, James R

In which patients is transcatheter aortic valve replacement potentially better indicated than surgery for redo aortic valve disease? Long-term results.

Transcatheter or Surgical Aortic Valve Replacement in Patients With Prior Coronary Artery Bypass Grafting John V. Conte, MD, Thomas G. Gleason, MD, Jon.

Relative amplitude index: A new tool for hemodynamic evaluation of periprosthetic regurgitation after transcatheter valve implantation Anneliese Heinz,

The effect of center volume on the incidence of postoperative complications and their impact on survival after lung transplantation Arman Kilic, MD,

Long-term prognosis of ascending aortic aneurysm after aortic valve replacement for bicuspid versus tricuspid aortic valve stenosis Evaldas Girdauskas,

Replacement of the ascending aorta in bicuspid aortic valve disease: Where do we draw the line? Thoralf M. Sundt, MD The Journal of Thoracic and Cardiovascular.

Isolated aortic valve replacement in North America comprising 108,687 patients in 10 years: Changes in risks, valve types, and outcomes in the Society.

Association between indices of prosthesis internal orifice size and operative mortality after isolated aortic valve replacement Charles R. Bridges, MD,

Reoperative “valve-in-valve” transapical transcatheter mitral valve replacement in a high-risk patient with a recent transapical transcatheter aortic.

It is still mostly about the mitral valve

Transapical Aortic Valve Replacement for Severe Aortic Stenosis: Results From the Nonrandomized Continued Access Cohort of the PARTNER Trial Todd M.

Jennifer S. Lawton, MD, Nader Moazami, MD, Michael K

Raghavendra Paknikar, BS, Jeffrey Friedman, BS, David Cron, BS, G

Joseph F. Sabik, MD, Vivek Rao, MD, PhD, Rüdiger Lange, MD, A

Risk-corrected impact of mechanical versus bioprosthetic valves on long-term mortality after aortic valve replacement Ole Lund, MD, PhD, Martin Bland,

The St Jude Medical Trifecta aortic pericardial valve: Results from a global, multicenter, prospective clinical study Joseph E. Bavaria, MD, Nimesh D.

Aortic and innominate routes for transcatheter aortic valve implantation Jean Porterie, MD, Nicolas Mayeur, MD, PhD, Thibaut Lhermusier, MD, PhD, Nicolas.

Management of dilated ascending aorta during aortic valve replacement: Valve replacement alone versus aorta wrapping versus aorta replacement Seung Hyun.

The risk and extent of neurologic events are equivalent for high-risk patients treated with transcatheter or surgical aortic valve replacement Thomas.

Transcatheter aortic valve replacement in intermediate-risk patients

Innovation and science: The future of valve design

Michele Gallo, MD, Gino Gerosa, MD

Transcatheter aortic valve replacement and surgical aortic valve replacement: Both excellent therapies J. James Edelman, MBBS(Hons), PhD, Vinod H. Thourani,

Subclavian/Axillary Access for Self-Expanding Transcatheter Aortic Valve Replacement Renders Equivalent Outcomes as Transfemoral Thomas G. Gleason, MD,

Delirium after surgical and transcatheter aortic valve replacement is associated with increased mortality Hersh S. Maniar, MD, Brian R. Lindman, MD,

The Journal of Thoracic and Cardiovascular Surgery

Conventional redo biological valve replacement over 20 years: Surgical benchmarks should guide patient selection for transcatheter valve-in-valve therapy

Fenton H. McCarthy, MD, MS, Nimesh D. Desai, MD, PhD

Niv Ad, MD, Lawrence M. Wei, MD

Daniel P. O’Hair, MD, Tanvir K. Bajwa, MD, Jeffrey J

TRANSFORM (Multicenter Experience With Rapid Deployment Edwards INTUITY Valve System for Aortic Valve Replacement) US clinical trial: Performance of a.

Commentary: Bioprosthetic aortic valve replacement: A high standard of comparison for transcatheter aortic valve implantation Aaron Martin, MD, Michael.

Passing the torch The Journal of Thoracic and Cardiovascular Surgery

Sutureless replacement versus transcatheter valve implantation in aortic valve stenosis: A propensity-matched analysis of 2 strategies in high-risk patients

Hans-Joachim Schäfers, MD

Transcatheter aortic valve replacement for prime time unrestricted distribution? Not so fast, my friend G. Michael Deeb, MD, John Carroll, MD The Journal.

The harder one looks, the more one finds

Concomitant replacement of the ascending aorta is free—for some

Jeffrey H. Shuhaiber, MD, Jeff Moore, MS, David B. Dyke, MD

The Journal of Thoracic and Cardiovascular Surgery

Discussion The Journal of Thoracic and Cardiovascular Surgery

Severe tricuspid or mitral regurgitation in inoperable patients with aortic stenosis. Can we leave them alone? Juan A. Crestanello, MD The Journal of.

Tissue valve, nitinol stent, or storage solution

Permanent pacemaker insertion following transcatheter aortic valve replacement: Not infrequent, not benign, and becoming predictable Craig M. Jarrett,

Commentary: When a choice is not an echo

Reliability of risk algorithms in predicting early and late operative outcomes in high-risk patients undergoing aortic valve replacement Todd M. Dewey,

Vinay Badhwar, MD, John S. Ikonomidis, MD, PhD, Jeffrey P. Jacobs, MD

“The more things change…”: The challenges ahead

Racing to the Rubicon Michael J. Reardon, MD, Vinod H. Thourani, MD

National trends in utilization and in-hospital outcomes of mechanical versus bioprosthetic aortic valve replacements Abby J. Isaacs, MS, Jeffrey Shuhaiber,

G. Chad Hughes, MD, Yue Zhao, PhD, J. Scott Rankin, MD, John E

Chordal replacement with polytetrafluoroethylene sutures for mitral valve repair: A 25- year experience Tirone E. David, MD, Susan Armstrong, MSc, Joan.

Contemporary outcomes of complete atrioventricular septal defect repair: Analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database

Durability of pericardial versus porcine bioprosthetic heart valves

Descending thoracic and thoracoabdominal aortic aneurysms: “Busted”

Zone zero thoracic endovascular aortic repair is all about “location, location, location” Kevin L. Greason, MD The Journal of Thoracic and Cardiovascular.

Presentation transcript:

Self-expanding transcatheter aortic valve replacement using alternative access sites in symptomatic patients with severe aortic stenosis deemed extreme risk of surgery Michael J. Reardon, MD, David H. Adams, MD, Joseph S. Coselli, MD, G. Michael Deeb, MD, Neal S. Kleiman, MD, Stan Chetcuti, MD, Steven J. Yakubov, MD, David Heimansohn, MD, James Hermiller, MD, G. Chad Hughes, MD, J. Kevin Harrison, MD, Kamal Khabbaz, MD, Peter Tadros, MD, George L. Zorn, MD, William Merhi, MD, John Heiser, MD, George Petrossian, MD, Newell Robinson, MD, Brijeshwar Maini, MD, Mubashir Mumtaz, MD, Joon Sup Lee, MD, Thomas G. Gleason, MD, Jon Resar, MD, John Conte, MD, Daniel Watson, MD, Sharla Chenoweth, MS, Jeffrey J. Popma, MD The Journal of Thoracic and Cardiovascular Surgery Volume 148, Issue 6, Pages 2869-2876.e7 (December 2014) DOI: 10.1016/j.jtcvs.2014.07.020 Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Study flow. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 2869-2876.e7DOI: (10.1016/j.jtcvs.2014.07.020) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Changes in mean aortic valve gradient (blue) and mean effective orifice area (red) during the study period at each follow-up point. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 2869-2876.e7DOI: (10.1016/j.jtcvs.2014.07.020) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure E1 CoreValve transcatheter heart valve. The self-expanding nitinol frame serves to anchor the transcatheter heart valve at the level of the aortic annulus. The supra-annular trileaflet porcine pericardial valve is hand sewn to the nitinol frame. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 2869-2876.e7DOI: (10.1016/j.jtcvs.2014.07.020) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure E2 Cumulative event curve for all-cause mortality or major stroke. Event rates were calculated using the Kaplan-Meier method. Brackets indicate 95% confidence intervals. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 2869-2876.e7DOI: (10.1016/j.jtcvs.2014.07.020) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure E3 New York Heart Association (NYHA) classification during the study period. Symptom status according to New York Heart Association class is shown at baseline and 30 days, 6 months, and 12 months for patients undergoing attempted transcatheter aortic valve replacement. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 2869-2876.e7DOI: (10.1016/j.jtcvs.2014.07.020) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure E4 Changes in paravalvular regurgitation during the study period. The percentage of patients by degree of paravalvular aortic regurgitation is shown at each follow-up interval. TAVR, Transcatheter aortic valve replacement. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 2869-2876.e7DOI: (10.1016/j.jtcvs.2014.07.020) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions