A.S. Aula, J. Töyräs, V. Tiitu, J.S. Jurvelin

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Presentation transcript:

Simultaneous ultrasound measurement of articular cartilage and subchondral bone A.S. Aula, J. Töyräs, V. Tiitu, J.S. Jurvelin Osteoarthritis and Cartilage Volume 18, Issue 12, Pages 1570-1576 (December 2010) DOI: 10.1016/j.joca.2010.09.009 Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 The anatomical locations of the test sites (numbers), reference and ultrasound (dot line) measurements in the medial tibial plateau of a bovine knee. The edge of the meniscus is illustrated with a dash line. Osteoarthritis and Cartilage 2010 18, 1570-1576DOI: (10.1016/j.joca.2010.09.009) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Typical ultrasound pulse-echo signal from an osteochondral sample. Signals from the cartilage and bone can be detected and separated for cartilage thickness down to 0.2mm. The present IRC time windows were chosen to include the whole reflection waveform from all samples: 0.8μs for IRCcart and 0.4μs for IRCbone. Time window for AIBcart was 0.4μs, which allowed use of a fixed time window also for the thinnest cartilage samples. Time window for AIBbone was 2μs. Osteoarthritis and Cartilage 2010 18, 1570-1576DOI: (10.1016/j.joca.2010.09.009) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Safranin-O stained histological sections across the medial tibial plateau demonstrate the spatial variation in structure and composition of cartilage and subchondral bone. Thicknesses of cartilage and subchondral plate can be seen to decrease towards the margin of the joint. Also the curvature of the medial plateau is well demonstrated in the figure. Osteoarthritis and Cartilage 2010 18, 1570-1576DOI: (10.1016/j.joca.2010.09.009) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions