Chronic Hepatitis B: Current Testing Strategies Robert G. Gish, Stephen A. Locarnini  Clinical Gastroenterology and Hepatology  Volume 4, Issue 6, Pages 666-676 (June 2006) DOI: 10.1016/j.cgh.2006.03.017 Copyright © 2006 American Gastroenterological Association Terms and Conditions

Figure 1 Dynamic range of commercially available quantitative HBV DNA assays.23 A variety of sensitive nucleic acid tests now are available to detect and quantify HBV DNA. The assays are available commercially and have been standardized to the WHO international reference standard.22 These assays include an improved chemiluminescent signal amplification assay and assays exploiting the greater dynamic range intrinsic to kinetic or real-time PCR. Reprinted with permission from Gish.24 Clinical Gastroenterology and Hepatology 2006 4, 666-676DOI: (10.1016/j.cgh.2006.03.017) Copyright © 2006 American Gastroenterological Association Terms and Conditions

Figure 2 The location of the major antiviral drug-resistant mutations associated with lamivudine (lmv), adefovir (adv), and entecavir (etv) resistance. Reprinted with permission from Locarnini.44 Clinical Gastroenterology and Hepatology 2006 4, 666-676DOI: (10.1016/j.cgh.2006.03.017) Copyright © 2006 American Gastroenterological Association Terms and Conditions