Correlation between dysplasia and mutations of six tumor suppressor genes in Barrett’s esophagus Siva Raja, BS, Sydney D Finkelstein, MD, Fabien K Baksh,

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Presentation transcript:

Correlation between dysplasia and mutations of six tumor suppressor genes in Barrett’s esophagus Siva Raja, BS, Sydney D Finkelstein, MD, Fabien K Baksh, MD, William E Gooding, MS, Patricia A Swalsky, BS, Tony E Godfrey, PhD, Percival O Buenaventura, MD, James D Luketich, MD The Annals of Thoracic Surgery Volume 72, Issue 4, Pages 1130-1135 (October 2001) DOI: 10.1016/S0003-4975(01)03005-3

Fig 1 (A) Hematoxylin and eosin–stained section of esophagus with microdissection of adenocarcinoma (A), crypt of Barrett’s esophagus (C), and normal skeletal muscle tissue (N). (B) Serial hematoxylin and eosin–stained sections showing crypt microdissection (arrow). The Annals of Thoracic Surgery 2001 72, 1130-1135DOI: (10.1016/S0003-4975(01)03005-3)

Fig 2 Typical autoradiograph showing the loss of heterozygosity (LOH) in a pentanucleotide polymorphism from a tumor sample (right) relative to a normal sample (left) from the same patient. The Annals of Thoracic Surgery 2001 72, 1130-1135DOI: (10.1016/S0003-4975(01)03005-3)