Efficacy of metformin therapy in adolescent girls with androgen excess: relation to sex hormone–binding globulin and androgen receptor polymorphisms

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Presentation transcript:

Efficacy of metformin therapy in adolescent girls with androgen excess: relation to sex hormone–binding globulin and androgen receptor polymorphisms Marta Díaz, Ph.D., Abel López-Bermejo, M.D., Ph.D., Clive J. Petry, Ph.D., Francis de Zegher, M.D., Ph.D., Lourdes Ibáñez, M.D., Ph.D. Fertility and Sterility Volume 94, Issue 7, Pages 2800-2803.e1 (December 2010) DOI: 10.1016/j.fertnstert.2010.06.083 Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

Distribution of SHBG (TAAAA)n (ns) and androgen receptor (AR) (CAG)n (P<.05) alleles in polycystic ovary syndrome (PCOS) (n = 70) and control (n = 107) girls. Fertility and Sterility 2010 94, 2800-2803.e1DOI: (10.1016/j.fertnstert.2010.06.083) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions