Volume 391, Issue 10120, Pages (February 2018)

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Volume 391, Issue 10120, Pages 572-580 (February 2018) Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals  Nathalie Conrad, MSc, Prof Andrew Judge, PhD, Jenny Tran, MSc, Hamid Mohseni, PhD, Deborah Hedgecott, BSc, Abel Perez Crespillo, BSc, Moira Allison, BSc, Prof Harry Hemingway, FRCP, Prof John G Cleland, MD, Prof John J V McMurray, MD, Prof Kazem Rahimi, FRCP  The Lancet  Volume 391, Issue 10120, Pages 572-580 (February 2018) DOI: 10.1016/S0140-6736(17)32520-5 Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 1 Overall and age-stratified heart failure incidence in 2002 versus 2014 (A) Number of cases of incident heart failure per 100 000 people in the European Standard Population. (B) Estimated absolute number of cases of incident heart failure in the UK population (based on census mid-year estimates). The Lancet 2018 391, 572-580DOI: (10.1016/S0140-6736(17)32520-5) Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 2 Temporal trends in comorbidities among patients diagnosed with incident heart failure, from 2002 to 2014 (A) Number of comorbidities, out of 17 major conditions, affecting patients with incident heart failure, over time. (B) Cumulative percentage of patients affected by individual comorbidities, over time. COPD=chronic obstructive pulmonary disease. The Lancet 2018 391, 572-580DOI: (10.1016/S0140-6736(17)32520-5) Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 3 Temporal trends in heart failure incidence by socioeconomic status quintile (2002–14) Age and sex-standardised incidence per 100 000 people by year and socioeconomic quintile are presented with fitted local polynomial regression lines and 95% CIs in grey. Socioeconomic quintile refers to Index of Multiple Deprivation 2015 quintile. The Lancet 2018 391, 572-580DOI: (10.1016/S0140-6736(17)32520-5) Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 4 Temporal trends in age at diagnosis of incident heart failure by socioeconomic status quintile (2002–14) Mean age at incident heart failure diagnosis by year and socioeconomic quintile is presented with fitted linear regression lines and 95% CIs in grey. Socioeconomic quintile refers to Index of Multiple Deprivation 2015 quintile. The Lancet 2018 391, 572-580DOI: (10.1016/S0140-6736(17)32520-5) Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

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