Volume 148, Issue 3, Pages e80-e85 (September 2015)

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Volume 148, Issue 3, Pages e80-e85 (September 2015) A 29-Year-Old Man With Nonproductive Cough, Exertional Dyspnea, and Chest Discomfort Darragh Halpenny, MD, James Suh, MD, Suzette Garofano, MD, Jeffrey Alpert, MD CHEST Volume 148, Issue 3, Pages e80-e85 (September 2015) DOI: 10.1378/chest.14-2936 Copyright © 2015 The American College of Chest Physicians Terms and Conditions

Figure 1 Posteroanterior chest radiograph demonstrating faint linear opacities in both lower zones. CHEST 2015 148, e80-e85DOI: (10.1378/chest.14-2936) Copyright © 2015 The American College of Chest Physicians Terms and Conditions

Figure 2 A-D, High-resolution CT scan images of the chest obtained at varying levels at the time of presentation, demonstrating basally predominant areas of predominantly subpleural ground-glass attenuation with mild subpleural reticulation. CHEST 2015 148, e80-e85DOI: (10.1378/chest.14-2936) Copyright © 2015 The American College of Chest Physicians Terms and Conditions

Figure 3 A, High-power image shows macrophages with fine cytoplasmic pigment within alveoli and focal mild interstitial chronic inflammation consisting of lymphocytes and a few eosinophils (hematoxylin and eosin [H&E], original magnification X 400). B, Low-power image shows diffusely abnormal lung parenchyma with abundant macrophages filling distal airways and alveolar spaces as well as scattered lymphoid aggregates (H&E, original magnification X 20). CHEST 2015 148, e80-e85DOI: (10.1378/chest.14-2936) Copyright © 2015 The American College of Chest Physicians Terms and Conditions

Figure 4 A-D, High-resolution CT scan images of the chest obtained at varying levels following 2 mo of steroid therapy, demonstrating considerable improvement in the previously identified areas of subpleural ground-glass attenuation. CHEST 2015 148, e80-e85DOI: (10.1378/chest.14-2936) Copyright © 2015 The American College of Chest Physicians Terms and Conditions