The Impact of Thymoma Histotype on Prognosis in a Worldwide Database

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The Impact of Thymoma Histotype on Prognosis in a Worldwide Database Cleo-Aron Weis, MD, MSc, Xiaopan Yao, PhD, Yanhong Deng, MPH, Frank C. Detterbeck, MD, Mirella Marino, MD, Andrew G. Nicholson, MD, James Huang, MD, Philipp Ströbel, MD, Alberto Antonicelli, MD, Alexander Marx, MD Journal of Thoracic Oncology Volume 10, Issue 2, Pages 367-372 (February 2015) DOI: 10.1097/JTO.0000000000000393 Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Stage distribution of thymoma histotypes. Stage classification as reported by the centers using either the Masaoka or Masoaka-Koga classification systems. WHO, World Health Organization. Journal of Thoracic Oncology 2015 10, 367-372DOI: (10.1097/JTO.0000000000000393) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Relative frequency of thymoma histotypes by center volume and geographic region. A, Frequency of thymoma subtypes, ordered by size of center and geographic region. B, The frequency of thymoma subtypes by region and by high- and low-volume centers. “High volume centers” are those contributing more than 50% of the total cases per region. WHO, World Health Organization. Journal of Thoracic Oncology 2015 10, 367-372DOI: (10.1097/JTO.0000000000000393) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Recurrence by thymoma histotype for specific stage groups. Cumulative incidence of recurrence by World Health organization (WHO) type (R0 patients) for (A) stages I + II, (B) stage III, and (C) stage IVa. Curves for stage IVb are not shown due to low case numbers. The table inserted in (A) shows pairwise comparisons for stages I + II with adjusted p values, asterisk denotes p ⩽ 0.05. Data for stages III and IVa are not shown because all results are nonsignificant. Journal of Thoracic Oncology 2015 10, 367-372DOI: (10.1097/JTO.0000000000000393) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions