Bioinformatics NTUEE B90901003 張林丞
What is Bioinformatics? The study and practice of applying data analysis to newly created and existing data from biological experiments. Take the advantage of powerful computation
What is Bioinformatics? Mathematics and Statistics Computer Science Biology
Central Paradigm
DNA Deoxyribonucleic Acid 4 letter alphabet {A,T,C,G}
DNA sequence analysis The sequence of ATCG
What’s the relation to information work? Database management Algorithm for sequence alignment and sequence searching
Protein information resource
Protein structure
Why protein sequence More useful information than DNA sequence But more complexity than DNA sequence Still DNA is the basis of bioinformatics
Example:第21型膠原蛋白基因 第21型膠原蛋白基因 心血管疾病 膠原蛋白分子 生醫材料
conclusion More and more applications
Reference http://brc.mcw.edu/AP/descriptions/bioinformatics.html 生物資訊入門 T.K. Attwood/D.J. Parry-Smith 藝軒圖書出版 http://www.itri.org.tw/chi/rnd/advanced_rnd/biotech_medicine/XE92-03.jsp