Off-Pump Coronary Artery Bypass Reduces Early Stroke in Octogenarians: A Meta- Analysis of 18,000 Patients Salah E. Altarabsheh, MD, Salil V. Deo, MS,

Slides:

Advertisements

Similar presentations

Surgical Versus Medical Therapy for Prosthetic Valve Endocarditis: A Meta-Analysis of 32 Studies Christos G. Mihos, DO, Romain Capoulade, PhD, Evin Yucel,

Advertisements

Assessment of the Association of Bilateral Internal Thoracic Artery Skeletonization and Sternal Wound Infection After Coronary Artery Bypass Grafting

Stroke/Death Rates Following Carotid Artery Stenting and Carotid Endarterectomy in Contemporary Administrative Dataset Registries: A Systematic Review

Elevated Hemoglobin A1c Is Associated With Lower Socioeconomic Position and Increased Postoperative Infections and Longer Hospital Stay After Cardiac.

Rapid deployment or sutureless versus conventional bioprosthetic aortic valve replacement: A meta-analysis Suk Ho Sohn, MD, Myoung-jin Jang, PhD, Ho.

Masatsugu Hamaji, MD, Syed Osman Ali, MD, Bryan M. Burt, MD

Equivalent outcomes after coronary artery bypass graft surgery performed by consultant versus trainee surgeons: A systematic review and meta-analysis

The prevalence of abdominal aortic aneurysm is consistently high among patients with coronary artery disease Jussi A. Hernesniemi, MD, PhD, Ville Vänni,

In Search of the Ideal Pulmonary Blood Source for the Norwood Procedure: A Meta- Analysis and Systematic Review Vikas Sharma, MBBS, Salil V. Deo, MBBS,

Preoperative Prophylactic Intraaortic Balloon Pump Reduces the Incidence of Postoperative Acute Kidney Injury and Short-Term Death of High-Risk Patients.

Elevated Hemoglobin A1c Is Associated With Lower Socioeconomic Position and Increased Postoperative Infections and Longer Hospital Stay After Cardiac.

Robert Brewer, MD, MHSA, Patricia F. Theurer, BSN, Chad M

Intraoperative Conversion From Off-Pump to On-Pump Coronary Artery Bypass Is Associated With Increased 30-Day Hospital Readmission Zhongmin Li, PhD,

Postoperative Atrial Fibrillation Prophylaxis After Lung Surgery: Systematic Review and Meta-Analysis Lars Peter Riber, MD, PhD, Torben Bjerregaard Larsen,

Homograft Implantation Techniques in the Aortic Position: To Preserve or Replace the Aortic Root? Thanos Athanasiou, MD, PhD, Catherine Jones, MBBS,

The Effectiveness of Postoperative Radiotherapy in Patients With Completely Resected Thymoma: A Meta-Analysis Dong Zhou, MD, Xu-Feng Deng, MD, Quan-Xing.

James Edgerton, MD, Giovanni Filardo, PhD, MPH, William H

Unprotected Left Main Coronary Artery Stenting Versus Coronary Artery Bypass Graft Surgery Hisato Takagi, MD, PhD, Hideaki Manabe, MD, Norikazu Kawai,

Long-Term Consequences of Postoperative Heart Failure After Surgery for Aortic Stenosis Compared With Coronary Surgery Farkas B. Vánky, MD, PhD, Erik.

Does Diabetes Affect the Postoperative Outcomes After Total Arterial Off-Pump Coronary Bypass Surgery in Multivessel Disease? Jae-Sung Choi, MD, PhD,

Comparing Long-Term Survival Between Patients Undergoing Off-Pump and On-Pump Coronary Artery Bypass Graft Operations Giovanni Filardo, PhD, MPH, Paul.

Association Between Obesity and Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Operations: A Systematic Review and Meta-Analysis Adrian.

Atrial Fibrillation After Coronary Artery Bypass Grafting Surgery: Development of a Predictive Risk Algorithm Mitchell J. Magee, MD, Morley A. Herbert,

The prevalence of abdominal aortic aneurysm is consistently high among patients with coronary artery disease Jussi A. Hernesniemi, MD, PhD, Ville Vänni,

Robert E. Freundlich, MD, MS, Michael D. Maile, MD, MS, Mark M

Off-Pump Versus On-Pump Coronary Revascularization: Meta-Analysis of Mid- and Long-Term Outcomes Umar A.R. Chaudhry, MBBS, Leanne Harling, MRCS, Christopher.

Long-Term Survival of Patients With Ischemic Cardiomyopathy Treated by Coronary Artery Bypass Grafting Versus Medical Therapy Eric J. Velazquez, MD,

Off-Pump Coronary Artery Bypass Surgery Versus Percutaneous Coronary Intervention: A Meta-Analysis of Randomized and Nonrandomized Studies J. James Edelman,

Surgical Versus Medical Therapy for Prosthetic Valve Endocarditis: A Meta-Analysis of 32 Studies Christos G. Mihos, DO, Romain Capoulade, PhD, Evin Yucel,

Right Gastroepiploic Artery Graft for Myocardial Revascularization: Prevalence of Atherosclerosis and Availability as a Conduit Kwang Ree Cho, MD, PhD,

Impact of Preoperative Angiotensin-Converting Enzyme Inhibitor Use on Clinical Outcomes After Cardiac Surgery Maral Ouzounian, MD, Karen J. Buth, MS,

Beating-Heart Versus Conventional On-Pump Coronary Artery Bypass Grafting: A Meta- Analysis of Clinical Outcomes Umar A.R. Chaudhry, MBBS, Leanne Harling,

Habib Jabagi, MD, MS, Diem T

Zheng-Zhe Feng, MD, Jian Shi, MD, Xue-Wei Zhao, MD, Zhi-Fei Xu, MD

Amedeo Anselmi, MD, Gianfederico Possati, MD, Mario Gaudino, MD

Ola A. Selnes, PhD, Maura A. Grega, MSN, Maryanne M

Intraoperative Temperature Control Using the Thermogard System During Off-pump Coronary Artery Bypass Grafting Gary S. Allen, MD The Annals of Thoracic.

A Meta-Analysis of Miniaturized Versus Conventional Extracorporeal Circulation in Valve Surgery Chuangshi Wang, MM, Kun Hua, PhD, Lu Yin, PhD, Yang Wang,

Mariano E. Brizzio, MD, Alex Zapolanski, MD, Richard E

Aortic Root Replacement With Biological Valved Conduits

A Systematic Review of Biocompatible Cardiopulmonary Bypass Circuits and Clinical Outcome Marco Ranucci, MD, Anna Balduini, AHA, Antonio Ditta, CCP,

Effects of Blood Transfusion on Cause-Specific Late Mortality After Coronary Artery Bypass Grafting—Less Is More Thomas A. Schwann, MD, Joseph R. Habib,

Off-pump coronary artery bypass grafting decreases risk-adjusted mortality and morbidity Joseph C Cleveland, MD, A.Laurie W Shroyer, PhD, Anita Y Chen,

Minimally Invasive Direct Coronary Artery Bypass Graft Surgery or Percutaneous Coronary Intervention for Proximal Left Anterior Descending Artery Stenosis:

Coronary Artery Bypass Grafting After Percutaneous Intervention Has Higher Early Mortality: A Meta-Analysis Salah E. Altarabsheh, MD, Salil V. Deo, MS,

Comparison of Conservative Treatment and Thymectomy on Myasthenia Gravis Outcome Emanuela Taioli, MD, PhD, Philip Kent Paschal, Bian Liu, PhD, Andrew.

Do the EXCEL and NOBLE Trial Results Change Meta-Analysis Findings?

Preoperative atrial fibrillation portends poor outcomes after coronary bypass graft surgery: A systematic review and meta-analysis Akshat Saxena, MBBS,

Meta-Analysis of Medium and Long-Term Efficacy of Loading Statins After Coronary Artery Bypass Grafting Cheng Bin, MM, Mu Junsheng, MD, Zhang Jianqun,

Yin-Shu Chang, MD, Jia-Xiang Wang, MD, PhD, Da-Wei Chang, PhD

Masatsugu Hamaji, MD, Syed Osman Ali, MD, Bryan M. Burt, MD

Coronary Artery Bypass Revascularization Using Bilateral Internal Thoracic Arteries in Diabetic Patients: A Systematic Review and Meta-Analysis Kan Kajimoto,

A Meta-Analysis of Postoperative Radiotherapy for Thymic Carcinoma

Red Blood Cell Transfusion Is Associated With Troponin Release After Elective Off- Pump Coronary Artery Bypass Surgery Fausto Biancari, MD, PhD, Eeva-Maija.

Hisato Takagi, MD, PhD, Takuya Umemoto, MD, PhD

Assessment of the Association of Bilateral Internal Thoracic Artery Skeletonization and Sternal Wound Infection After Coronary Artery Bypass Grafting

Limitations of Hospital Volume as a Measure of Quality of Care for Coronary Artery Bypass Graft Surgery Karl F. Welke, MD, Mitchell J. Barnett, PharmD,

What Is the Role of Minimally Invasive Mitral Valve Surgery in High-Risk Patients? A Meta-Analysis of Observational Studies Marco Moscarelli, MD, Khalil.

First Report on 30-day and Operative Mortality in Risk Model of Isolated Coronary Artery Bypass Grafting in Japan Noboru Motomura, MD, PhD, Hiroaki Miyata,

Preoperative Intraaortic Balloon Pump Enhances Cardiac Performance and Improves the Outcome of Redo CABG Jan T. Christenson, MD, PhD, Pierre Badel, MD,

Trends in Patient Characteristics and Outcomes of Coronary Artery Bypass Grafting in the 2000 to 2012 Medicare Population Christian McNeely, MD, Stephen.

On-Pump Versus Off-Pump Surgical Revascularization for Left Main Stem Stenosis: Risk Adjusted Outcomes John C.Y. Lu, Antony D. Grayson, BS, D. Mark Pullan

Sagar U. Nigwekar, MD, Praveen Kandula, MD, MPH

Predicting Early Coronary Artery Bypass Graft Failure by Intraoperative Transit Time Flow Measurement Yoshiyuki Tokuda, MD, Min-Ho Song, MD, PhD, Yuichi.

Increased Rehospitalization Rate After Coronary Bypass Operation for Acute Coronary Syndrome: A Prospective Study in 200 Patients Staffan Bjessmo, MD,

Dumbor L. Ngaage, MD, FRCS (C-Th), Michael E. Cowen, FRCS

Hisato Takagi, MD, PhD, Masafumi Matsui, MD, Takuya Umemoto, MD, PhD

Influence of On-Pump Versus Off-Pump Techniques and Completeness of Revascularization on Long-Term Survival After Coronary Artery Bypass Omar M. Lattouf,

Mary E. Plomondon, PhD, Adrianne W. Casebeer, PhD, Lynn M

Magnus Dalén, MD, Torbjörn Ivert, MD, PhD, Martin J

Presentation transcript:

Off-Pump Coronary Artery Bypass Reduces Early Stroke in Octogenarians: A Meta- Analysis of 18,000 Patients Salah E. Altarabsheh, MD, Salil V. Deo, MS, MCh, Abeer M. Rababa'h, PhD, Ju Yong Lim, MD, Yang Hyun Cho, MD, Vikas Sharma, MD, Sung Ho Jung, MD, Euisoo Shin, MD, Alan H. Markowitz, MD, Soon J. Park, MD The Annals of Thoracic Surgery Volume 99, Issue 5, Pages 1568-1575 (May 2015) DOI: 10.1016/j.athoracsur.2014.12.057 Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Flow chart depicting study selection for meta-analysis. (Adapted from Moher D, Liberati A, Tetzlaff J, Altman DG, The PRISMA Group (2009). Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. PLoS Med 6:e1000097.) The Annals of Thoracic Surgery 2015 99, 1568-1575DOI: (10.1016/j.athoracsur.2014.12.057) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 The pooled result demonstrates that patients undergoing off-pump coronary artery bypass grafting (OPCABG) had a significantly fewer number of grafts than did patients in the on-pump CABG (ONCABG) cohort (mean difference, –0.52 [–0.83 to –0.20]). (CI = confidence interval; SD = standard deviation.) The Annals of Thoracic Surgery 2015 99, 1568-1575DOI: (10.1016/j.athoracsur.2014.12.057) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 (A) Funnel plot demonstrating publication bias. (B) Adjusted Forest plot of pooled result for early mortality using the trim-fill method. (RR = risk ratio; seTE = standard error for treatment estimate; TE = treatment estimate.) The Annals of Thoracic Surgery 2015 99, 1568-1575DOI: (10.1016/j.athoracsur.2014.12.057) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 (A) Funnel plot demonstrates publication bias for the analysis of stroke (p = 0.01). (B) The adjusted Forest plot demonstrates that off-pump coronary artery bypass grafting (OPCABG) has a lower stroke risk than on-pump CABG (ONCABG). (RR = risk ratio; seTE = standard error for treatment estimate; TE = treatment estimate.) The Annals of Thoracic Surgery 2015 99, 1568-1575DOI: (10.1016/j.athoracsur.2014.12.057) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 (A) Forest plot for respiratory failure demonstrates that off-pump coronary artery bypass grafting (OPCABG) is better than on-pump CABG (ONCABG). (B) Cumulative meta-analysis demonstrates that the resultant heterogeneity (I2 ) is caused by adding Cavallaro and colleagues to the pooled result. (RR = risk ratio.) The Annals of Thoracic Surgery 2015 99, 1568-1575DOI: (10.1016/j.athoracsur.2014.12.057) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 Forest plot for postoperative atrial fibrillation demonstrates that rates are comparable in both cohorts (p = 0.27). The Annals of Thoracic Surgery 2015 99, 1568-1575DOI: (10.1016/j.athoracsur.2014.12.057) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions