Need for better diabetes treatment for improved renal outcome Peter Rossing, Dick de Zeeuw  Kidney International  Volume 79, Pages S28-S32 (March 2011) DOI: 10.1038/ki.2010.513 Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 1 Incidence of end-stage renal disease in the United States by diagnosis.5 USRDS, United States Renal Data System. Kidney International 2011 79, S28-S32DOI: (10.1038/ki.2010.513) Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 2 Comparing the effect of conventional versus optimal drug intervention for renal outcome at different stages of type 2 diabetes.18 Copyright 2009, Touch Briefings. Kidney International 2011 79, S28-S32DOI: (10.1038/ki.2010.513) Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 3 Outcome of the Steno-2 trial of 160 microalbuminuric type 2 diabetic patients randomized to intensive multifactorial intervention or conventional therapy. (a) Prevalence of patients reaching treatment target after 8 years of intervention and (b) development of fatal and non-fatal cardiovascular (CV) end points in the two groups (hazards ratio 0.47, P=0.007).20 Copyright 2003, Massachusetts Medical Society. Kidney International 2011 79, S28-S32DOI: (10.1038/ki.2010.513) Copyright © 2011 International Society of Nephrology Terms and Conditions