Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data.

Slides:



Advertisements
Similar presentations
Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis A. Loyola-Sánchez, J. Richardson, N.J.
Advertisements

Anatomical alignment, but not goniometry, predicts femorotibial cartilage loss as well as mechanical alignment  R. Moyer, W. Wirth, F. Eckstein  Osteoarthritis.
Anatomical alignment, but not goniometry, predicts femorotibial cartilage loss as well as mechanical alignment: data from the Osteoarthritis Initiative 
Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data.
Subregional laminar cartilage MR spin–spin relaxation times (T2) in osteoarthritic knees with and without medial femorotibial cartilage loss – data from.
Subchondral bone marrow lesions are highly associated with, and predict subchondral bone attrition longitudinally: the MOST study  F.W. Roemer, T. Neogi,
Two year longitudinal change and test–retest-precision of knee cartilage morphology in a pilot study for the osteoarthritis initiative  F. Eckstein, M.D.,
Predictive validity of within-grade scoring of longitudinal changes of MRI-based cartilage morphology and bone marrow lesion assessment in the tibio-femoral.
Validity and sensitivity to change of three scales for the radiographic assessment of knee osteoarthritis using images from the Multicenter Osteoarthritis.
Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort  W. Wirth, M.S., M.-P. Hellio.
Associations between pre-operative radiographic changes and outcomes after total knee joint replacement for osteoarthritis  M.M. Dowsey, M. Nikpour, P.
Osteoarthritis as a disease of mechanics
Reference values and Z-scores for subregional femorotibial cartilage thickness – results from a large population-based sample (Framingham) and comparison.
Cyst-like lesions of the knee joint and their relation to incident knee pain and development of radiographic osteoarthritis: the MOST study  A. Guermazi,
Association of knee pain with a reduction in thigh muscle strength – a cross-sectional analysis including 4553 osteoarthritis initiative participants 
Sensitivity to Change of 3D Meniscal Measures in Rapidly Progressing Knee Osteoarthritis and Association With Radiographic Joint Space Width Loss  M.
Osteoarthritis year 2011 in review: biochemical markers of osteoarthritis: an overview of research and initiatives  Y. Henrotin  Osteoarthritis and Cartilage 
Predictive and concurrent validity of cartilage thickness change as a marker of knee osteoarthritis progression: data from the Osteoarthritis Initiative 
A new non-invasive method to assess synovitis severity in relation to symptoms and cartilage volume loss in knee osteoarthritis patients using MRI  J.-P.
Presence, location, type and size of denuded areas of subchondral bone in the knee as a function of radiographic stage of OA – data from the OA initiative 
Longitudinal change in thigh muscle strength prior to and concurrent with symptomatic and radiographic knee osteoarthritis progression: data from the.
Radiographic and MRI assessment in osteoarthritis efficacy studies and anti-nerve growth factor programs: Characteristics and differences  A. Guermazi,
The course of ultrasonographic abnormalities in knee osteoarthritis: 1 year follow up  K. Bevers, J.W.J. Bijlsma, J.E. Vriezekolk, C.H.M. van den Ende,
Comparison of load responsiveness of cartilage T1rho and T2 in porcine knee joints: an experimental loading MRI study  H. Hamada, T. Nishii, S. Tamura,
Vastus lateralis/vastus medialis cross-sectional area ratio impacts presence and degree of knee joint abnormalities and cartilage T2 determined with 3T.
Pain has a stronger association with thigh muscle strength than the radiographic stage of knee osteoarthritis - data from the Osteoarthritis Initiative 
Evaluations of radiographic joint space – do they adequately predict cartilage conditions in the patellofemoral joint of the patients undergoing total.
Subregional femorotibial cartilage morphology in women – comparison between healthy controls and participants with different grades of radiographic knee.
Baseline and longitudinal change in isometric muscle strength prior to radiographic progression in osteoarthritic and pre-osteoarthritic knees – data.
Osteoarthritis may not be a one-way-road of cartilage loss – comparison of spatial patterns of cartilage change between osteoarthritic and healthy knees 
Comparison of 1-year vs 2-year change in regional cartilage thickness in osteoarthritis results from 346 participants from the Osteoarthritis Initiative 
Anatomical alignment, but not goniometry, predicts femorotibial cartilage loss as well as mechanical alignment: data from the Osteoarthritis Initiative 
Medial arch supports do not significantly alter the knee adduction moment in people with knee osteoarthritis  R.S. Hinman, L. Bardin, M. Simic, K.L. Bennell 
S. Muraki, T. Akune, Y. En-yo, M. Yoshida, T. Suzuki, H. Yoshida, H
Bone marrow lesions and joint effusion are strongly and independently associated with weight-bearing pain in knee osteoarthritis: data from the osteoarthritis.
Direct comparison of fixed flexion, radiography and MRI in knee osteoarthritis: responsiveness data from the Osteoarthritis Initiative  W. Wirth, J. Duryea,
Rates and sensitivity of knee cartilage thickness loss in specific central reading radiographic strata from the osteoarthritis initiative  S. Maschek,
N. Segal, E. Frick, M. Nevitt, J. Torner, D. Felson, A. Guermazi, D
Role of physical activity in cartilage damage progression of subjects with baseline full- thickness cartilage defects in medial tibiofemoral compartment:
Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis  M. Blagojevic, C. Jinks, A. Jeffery, K.P.
G. Neumann, D. Hunter, M. Nevitt, L. B. Chibnik, K. Kwoh, H. Chen, T
A graphic user interface for the evaluation of knee osteoarthritis (GEKO): an open- source tool for histological grading  H.E. Kloefkorn, B.Y. Jacobs,
Quantitative measurement of medial femoral knee cartilage volume – analysis of the OA Biomarkers Consortium FNIH Study cohort  L.F. Schaefer, M. Sury,
Baseline radiographic osteoarthritis and semi-quantitatively assessed meniscal damage and extrusion and cartilage damage on MRI is related to quantitatively.
Who should have a joint replacement? A plea for more ‘phronesis’
How do short-term rates of femorotibial cartilage change compare to long-term changes? Four year follow-up data from the osteoarthritis initiative  F.
Progression of cartilage damage and meniscal pathology over 30 months is associated with an increase in radiographic tibiofemoral joint space narrowing.
A reference database of cartilage 3 T MRI T2 values in knees without diagnostic evidence of cartilage degeneration: data from the osteoarthritis initiative 
Elevated cartilage T2 and increased severity of cartilage defects at baseline are associated with the development of knee pain over 7 years  G.B. Joseph,
D.J. Hunter  Osteoarthritis and Cartilage 
Cartilage thickness loss and clinical worsening are associated in osteoarthritic knees reaching virtual replacement status – A nested case control study.
Prospective change in daily walking over 2 years in older adults with or at risk of knee osteoarthritis: the MOST study  D.K. White, C. Tudor-Locke, Y.
Synovitis and the risk of knee osteoarthritis: the MOST Study
Baseline trabecular bone and its relation to incident radiographic knee osteoarthritis and increase in joint space narrowing score: directional fractal.
C. Ratzlaff, M. Koehoorn, J. Cibere, J. Kopec 
Location-specific hip joint space width for progression of hip osteoarthritis: predictive validity and responsiveness of a new computerized measure  C.
I. G. Otterness, Ph. D. , M. -P. H. Le Graverand, M. D. , Ph. D. , F
Magnitude and regional distribution of cartilage loss associated with grades of joint space narrowing in radiographic osteoarthritis – data from the Osteoarthritis.
Osteoarthritis year 2012 in review: biology
Knee cartilage defects in a sample of older adults: natural history, clinical significance and factors influencing change over 2.9 years  J. Carnes, O.
Location-specific hip joint space width for progression of hip osteoarthritis – Data from the Osteoarthritis Initiative  C. Ratzlaff, C. Van Wyngaarden,
Association of hip and pelvic geometry with tibiofemoral osteoarthritis: Multicenter Osteoarthritis Study (MOST)  A. Boissonneault, J.A. Lynch, B.L. Wise,
Trajectory of cartilage loss within 4 years of knee replacement – a nested case–control study from the Osteoarthritis Initiative  F. Eckstein, R.M. Boudreau,
R. B. Souza, C. Stehling, B. T. Wyman, M. -P. Hellio Le Graverand, X
M. Hudelmaier, W. Wirth  Osteoarthritis and Cartilage 
MRI-based extended ordered values more efficiently differentiate cartilage loss in knees with and without joint space narrowing than region-specific approaches.
Is the atrophic phenotype of tibiofemoral osteoarthritis associated with faster progression of disease? The MOST study  M.D. Crema, D.T. Felson, A. Guermazi,
M. Doherty, P. Dieppe  Osteoarthritis and Cartilage 
Tibial coverage, meniscus position, size and damage in knees discordant for joint space narrowing – data from the Osteoarthritis Initiative  K. Bloecker,
General Information Osteoarthritis and Cartilage
Presentation transcript:

Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data from the Osteoarthritis Initiative  W. Wirth, M. Nevitt, M.-P. Hellio Le Graverand, J. Lynch, S. Maschek, M. Hudelmaier, F. Eckstein  Osteoarthritis and Cartilage  Volume 22, Issue 1, Pages 63-70 (January 2014) DOI: 10.1016/j.joca.2013.10.011 Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 MC and 95% CIs of the change in cartilage thickness in knees without JSN (noJSN), with lateral JSN 1–3 (latJSN), and with medial JSN 1–3 (medJSN) in A) the LFTC and B) the MFTC. Osteoarthritis and Cartilage 2014 22, 63-70DOI: (10.1016/j.joca.2013.10.011) Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 MC in ordered values 1–16 (OV 1–OV 16) in knees without JSN (noJSN), with lateral JSN 1–3 (latJSN 1–3), and with medial JSN 1–3 (medJSN 1–3). Osteoarthritis and Cartilage 2014 22, 63-70DOI: (10.1016/j.joca.2013.10.011) Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions