Magnetic resonance imaging lesions are more severe and cartilage T2 relaxation time measurements are higher in isolated lateral compartment radiographic.

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Presentation transcript:

Magnetic resonance imaging lesions are more severe and cartilage T2 relaxation time measurements are higher in isolated lateral compartment radiographic knee osteoarthritis than in isolated medial compartment disease – data from the Osteoarthritis Initiative B.L. Wise, J. Niu, A. Guermazi, F. Liu, U. Heilmeier, E. Ku, J.A. Lynch, Y. Zhang, D.T. Felson, C.K. Kwoh, N.E. Lane Osteoarthritis and Cartilage Volume 25, Issue 1, Pages 85-93 (January 2017) DOI: 10.1016/j.joca.2016.08.002 Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Study design flowchart for subject/knee inclusion. Osteoarthritis and Cartilage 2017 25, 85-93DOI: (10.1016/j.joca.2016.08.002) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Representative 3 T Knee MRI images illustrating the most prominent knee pathologies observed in patients with IL-ROA. Image to the left (sag 3D DESS sequence): shows a severe cartilage lesion involving the lateral posterior femoral condyle. Middle image (sag Fat suppressed TSE sequence): depicts a severe lateral femoral bone marrow lesion. Image to the right (Sag Fat suppressed TSE): shows a lateral meniscal tear involving the anterior and posterior horn. Osteoarthritis and Cartilage 2017 25, 85-93DOI: (10.1016/j.joca.2016.08.002) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Representative cartilage T2 color maps of the lateral tibia shown for a subject with IL-ROA (on the left), a subject with IM-ROA (middle) and a control subject (on the right). Cartilage T2 color maps were overlaid on the first-echo images of the multislice multiecho (MSME) sequence. T2 values are displayed on a voxel by voxel basis. Blue voxels indicate low cartilage T2 values, red voxels signify high cartilage T2 values. Subjects with IL-ROA showed significantly higher mean T2 values than subjects with IM-ROA or controls (P < 0.001). Osteoarthritis and Cartilage 2017 25, 85-93DOI: (10.1016/j.joca.2016.08.002) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions