Thermogenesis by THADA

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Thermogenesis by THADA Nirmalya Chatterjee, Norbert Perrimon Developmental Cell Volume 41, Issue 1, Pages 1-2 (April 2017) DOI: 10.1016/j.devcel.2017.03.021 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 Non-shivering Thermogenesis Triggered by THADA SERCA uses the energy of ATP hydrolysis to pump Ca2+ into the ER lumen. THADA uncouples ATP hydrolysis from Ca2+ transport, and that results in reduced Ca2+ transport into ER and in thermogenesis due to dissipation of the energy from ATP hydrolysis in the form of heat. Developmental Cell 2017 41, 1-2DOI: (10.1016/j.devcel.2017.03.021) Copyright © 2017 Elsevier Inc. Terms and Conditions