Finding the ideal biomaterial for aortic valve repair with ex vivo porcine left heart simulator and finite element modeling Hadi Daood Toeg, MD, MSc,

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Presentation transcript:

Finding the ideal biomaterial for aortic valve repair with ex vivo porcine left heart simulator and finite element modeling Hadi Daood Toeg, MD, MSc, Ovais Abessi, MEng, Talal Al-Atassi, MD, MPH, Laurent de Kerchove, MD, Gebrine El-Khoury, MD, Michel Labrosse, PhD, Munir Boodhwani, MD, MMSc The Journal of Thoracic and Cardiovascular Surgery Volume 148, Issue 4, Pages 1739-1745.e1 (October 2014) DOI: 10.1016/j.jtcvs.2014.05.004 Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Representative circumferential and radial stress–strain properties of the original leaflets and corresponding biomaterials derived from equibiaxial planar testing (Cauchy stress, kPa; Green strain, %). Original, Native unrepaired valve; Rad, radial direction; Circ, circumferential direction; APP, autologous porcine pericardium; HEM, Hemashield; CorM, CorMatrix; BPP, bovine pericardial patch; SJM, St Jude Medical patch. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 1739-1745.e1DOI: (10.1016/j.jtcvs.2014.05.004) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Illustration of the Von Mises stresses on the replaced cusps (noncoronary cusp [NCC]) with finite element modeling demonstrating (A) native unrepaired valve; B, autologous porcine pericardium (APP), and (C) Hemashield (HEM). Blue areas represent minimal to no stress (0 kPa); light blue, green, and yellow represent increasing levels of stress (maximum 7.774 kPa). Increased maximal stress was seen at the suture lines in the replaced NCCs for (B) APP, and (C) HEM compared with the (A) native unrepaired valve. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 1739-1745.e1DOI: (10.1016/j.jtcvs.2014.05.004) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions