Keratosis follicularis spinulosa decalvans in a family

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Presentation transcript:

Keratosis follicularis spinulosa decalvans in a family Jane S. Bellet, MD, Andrew L. Kaplan, MD, M. Angelica Selim, MD, Elise A. Olsen, MD Journal of the American Academy of Dermatology Volume 58, Issue 3, Pages 499-502 (March 2008) DOI: 10.1016/j.jaad.2007.03.028 Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Proband's face demonstrating erythema and alopecia of the eyebrows. Inset: Proband's scalp with innumerable hyperkeratotic follicularly based nodules with surrounding erythema. Journal of the American Academy of Dermatology 2008 58, 499-502DOI: (10.1016/j.jaad.2007.03.028) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Proband's sister with macular erythema over the brows and cheeks. Inset: Diffuse perifollicular erythema with scaling, but without scarring alopecia, on the scalp of the proband's sister. Journal of the American Academy of Dermatology 2008 58, 499-502DOI: (10.1016/j.jaad.2007.03.028) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Representative scalp biopsy specimens demonstrate (A) concentric perifollicular fibrosis at the level of the follicular infundibulum with moderately dense lymphocytic inflammatory cell infiltrate (horizontal section). At higher magnification (B) dilatation of the follicular infundibulum with follicular plugging can be seen (vertical section). At still higher magnification (C), thinning/degeneration of the inner root sheath above Adamson's fringe with protrusion of the outer root sheath into the follicular canal (arrow) can be seen (horizontal section). (A-C, Hematoxylin-stain; original magnifications: A, ×4; B, ×10; C, ×20.) Journal of the American Academy of Dermatology 2008 58, 499-502DOI: (10.1016/j.jaad.2007.03.028) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions