Cost Effectiveness of Dulaglutide Compared with Liraglutide and Glargine in Type 2 Diabetes Mellitus Patients in Colombia  Pieralessandro Lasalvia, Laura.

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Cost Effectiveness of Dulaglutide Compared with Liraglutide and Glargine in Type 2 Diabetes Mellitus Patients in Colombia  Pieralessandro Lasalvia, Laura Baquero, Margarita Otálora-Esteban, MD, Camilo Castañeda-Cardona, MD, Diego Rosselli, MD, MSc, MEd  Value in Health Regional Issues  Volume 14, Pages 35-40 (December 2017) DOI: 10.1016/j.vhri.2016.10.006 Copyright © 2017 Terms and Conditions

Fig. 1 Markov model used in the estimation. All patients are assumed to start in the “No complications” state. Value in Health Regional Issues 2017 14, 35-40DOI: (10.1016/j.vhri.2016.10.006) Copyright © 2017 Terms and Conditions

Fig. 2 Tornado diagram showing univariate sensitivity analysis for base-case scenario. A: nondaily injection utility; B: age; C: monthly dulaglutide cost; D: retinopathy utility; E: monthly retinopathy cost; F: % achieving <7% HbA1c with glargine; G: monthly nephropathy cost; H: nephropathy utility; I: monthly glucometries; J: cost per glucometry; K: utility per BMI unit change; L: IU/kg of glargine; M: daily glargine IU; N: weight; O: % achieving <7% HbA1c with dulaglutide; P: nephropathy and retinopathy utility; Q: cost per IU of glargine; R: hypoglycemia utility; S: hypoglycemia cost. BMI, body mass index; HbA1c, glycated hemoglobin; IU, international unit; USD, US dollars. Value in Health Regional Issues 2017 14, 35-40DOI: (10.1016/j.vhri.2016.10.006) Copyright © 2017 Terms and Conditions

Fig. 3 Scatterplot showing probabilistic analysis performed by running 1000 Monte-Carlo simulations for the comparison between dulaglutide and glargine. The diagonal line indicates the cost-effectiveness threshold of $17,270 (3 times the Colombian per capita gross domestic product). ICE, incremental cost-effectiveness; QALY, quality-adjusted life-year. Value in Health Regional Issues 2017 14, 35-40DOI: (10.1016/j.vhri.2016.10.006) Copyright © 2017 Terms and Conditions

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