Utility of age-specific serum anti-Müllerian hormone concentrations

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Utility of age-specific serum anti-Müllerian hormone concentrations David H. Barad, Andrea Weghofer, Norbert Gleicher Reproductive BioMedicine Online Volume 22, Issue 3, Pages 284-291 (March 2011) DOI: 10.1016/j.rbmo.2010.12.002 Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 Age-specific anti-Müllerian hormone (AMH) and FSH concentrations relating to age of 792 women with FSH <12mIU/ml and oestradiol ⩽80pg/ml. Values are means and 95% CI. Reproductive BioMedicine Online 2011 22, 284-291DOI: (10.1016/j.rbmo.2010.12.002) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

Figure 2 Definition of age-specific anti-Müllerian hormone (AMH) relating to age of 792 women with FSH <12mIU/ml and oestradiol ⩽80pg/ml. Values are median (lines), 25–75th centile (boxes) and 95% CI (whiskers). AMH concentrations declined significantly with age (P<0.001). Table 2 summarizes lower and upper cutoff values at various ages. Circles=outliers; stars=extreme outliers. Reproductive BioMedicine Online 2011 22, 284-291DOI: (10.1016/j.rbmo.2010.12.002) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

Figure 3 Oocyte yields at different ages and anti-Müllerian hormone (AMH) concentrations. (A) Oocyte yields among 442 women who underwent IVF with normal and high AMH (green) and abnormally low AMH (blue); ∗Significant differences within each age group are based on the Mann Whitney U-test (P<0.05). (B) Oocyte yields in each age group based on abnormally low (blue), normal (green) and abnormally high (beige) as-AMH concentrations. Normal was defined as within the 25–75th centiles for a given age group; ∗Significant differences from normal within each age group (P<0.05). Table 3 gives further statistical details. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.) Reproductive BioMedicine Online 2011 22, 284-291DOI: (10.1016/j.rbmo.2010.12.002) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions