Oncological Characteristics of Radiological Invasive Adenocarcinoma with Additional Ground-Glass Nodules on Initial Thin-Section Computed Tomography:

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Oncological Characteristics of Radiological Invasive Adenocarcinoma with Additional Ground-Glass Nodules on Initial Thin-Section Computed Tomography: Comparison with Solitary Invasive Adenocarcinoma Aritoshi Hattori, MD, Takeshi Matsunaga, MD, Kazuya Takamochi, MD, Shiaki Oh, MD, Kenji Suzuki, MD Journal of Thoracic Oncology Volume 11, Issue 5, Pages 729-736 (May 2016) DOI: 10.1016/j.jtho.2016.01.008 Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Figure 1 A radiologically invasive tumor was defined as a lung tumor with a consolidation tumor ratio (CTR) of at least 0.5 but no greater than 1.0. A part solid tumor was defined as a lung tumor with a ground-glass opacity component (i.e., 0.5 ≤ CTR < 1.0) (left), whereas pure solid tumor was defined as a tumor showing consolidation only and without ground-glass opacity on thin-section computed tomography (i.e., CTR = 1.0) (right). Journal of Thoracic Oncology 2016 11, 729-736DOI: (10.1016/j.jtho.2016.01.008) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Figure 2 Additional ground-glass nodules (GGNs) were tentatively defined as any lung nodule with a pure GGN or GGN-predominant appearance showing a smaller diameter than that of the main tumor that was detected in the initial survey for radiological invasive adenocarcinoma on thin-section computed tomography scan (yellow circle). Journal of Thoracic Oncology 2016 11, 729-736DOI: (10.1016/j.jtho.2016.01.008) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Figure 3 Overall survival is shown for patients with clinical stage T1N0M0 radiological invasive adenocarcinoma with or without additional ground-glass nodules (AGGNs). The 5-year overall survival rate for patients with AGGNs was 92.2% (red line), and for those without AGGNs, it was 79.9% (black line), showing a significant difference between the two study arms (p = 0.0323). Journal of Thoracic Oncology 2016 11, 729-736DOI: (10.1016/j.jtho.2016.01.008) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions