Prognostic Factors in Completely Resected Node-Negative Lung Adenocarcinoma of 3 cm or Smaller Jung-Jyh Hung, MD, PhD, Yi-Chen Yeh, MD, Yu-Chung Wu,

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Prognostic Factors in Completely Resected Node-Negative Lung Adenocarcinoma of 3 cm or Smaller Jung-Jyh Hung, MD, PhD, Yi-Chen Yeh, MD, Yu-Chung Wu, MD, Teh-Ying Chou, MD, PhD, Wen-Hu Hsu, MD Journal of Thoracic Oncology Volume 12, Issue 12, Pages 1824-1833 (December 2017) DOI: 10.1016/j.jtho.2017.07.009 Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

Figure 1 Cumulative probability of overall survival (A) and freedom from recurrence (B) in 726 patients with resected node-negative lung adenocarcinoma 3 cm or smaller. Journal of Thoracic Oncology 2017 12, 1824-1833DOI: (10.1016/j.jtho.2017.07.009) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

Figure 2 Kaplan-Meier analysis (log-rank test) for probability of freedom from recurrence in patients of resected node-negative lung adenocarcinoma 3 cm or smaller (A and B) or 2 cm or smaller (C and D). (A) Probability of freedom from recurrence according to predominant pattern group (lepidic/acinar/papillary versus micropapillary/solid predominant). (B) The patients were divided into three groups according to number of positive risk predictors (tumor >2 but ≤3 cm and micropapillary/solid predominant pattern): no or one positive risk predictor (group 1), and two positive risk predictors (group 2). Patients with both positive risk predictors had significantly higher probability of recurrence. (C) Probability of freedom from recurrence according to presence of solid pattern. (D) The patients were divided into two groups according to number of positive risk predictors (tumor >1 cm but ≤2 cm and presence of solid pattern): no or one positive risk predictor (group 1), and two positive risk predictors (group 2). Patients with both positive risk predictors had a significantly higher probability of recurrence. Journal of Thoracic Oncology 2017 12, 1824-1833DOI: (10.1016/j.jtho.2017.07.009) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions