Robin L. Holland, Steven R. Blanke Cell Host & Microbe

Slides:

Advertisements

Similar presentations

How T Cells Earn the Follicular Rite of Passage Carola G. Vinuesa, Jason G. Cyster Immunity Volume 35, Issue 5, Pages (November 2011) DOI: /j.immuni

Advertisements

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Mitoconfusion: Noncanonical Functioning of Dynamism Factors in Static Mitochondria of the Heart Moshi Song, Gerald W. Dorn Cell Metabolism Volume 21, Issue.

Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni

The Pathobiology of Vascular Dementia Costantino Iadecola Neuron Volume 80, Issue 4, Pages (November 2013) DOI: /j.neuron Copyright.

Human Gut Microbes Use Multiple Transporters to Distinguish Vitamin B12 Analogs and Compete in the Gut Patrick H. Degnan, Natasha A. Barry, Kenny C. Mok,

An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan,

Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis Wing-Hang Tong, Tracey A. Rouault Cell.

Low-Abundance Biofilm Species Orchestrates Inflammatory Periodontal Disease through the Commensal Microbiota and Complement George Hajishengallis, Shuang.

Nucleocapsid Phosphorylation and RNA Helicase DDX1 Recruitment Enables Coronavirus Transition from Discontinuous to Continuous Transcription Chia-Hsin.

The Monarch Butterfly Genome Yields Insights into Long-Distance Migration Shuai Zhan, Christine Merlin, Jeffrey L. Boore, Steven M. Reppert Cell Volume.

Genes Induced Late in Infection Increase Fitness of Vibrio cholerae after Release into the Environment Stefan Schild, Rita Tamayo, Eric J. Nelson, Firdausi.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.

A View to a Kill: The Bacterial Type VI Secretion System Brian T. Ho, Tao G. Dong, John J. Mekalanos Cell Host & Microbe Volume 15, Issue 1, Pages 9-21.

The Mitochondrial Basis of Aging Nuo Sun, Richard J. Youle, Toren Finkel Molecular Cell Volume 61, Issue 5, Pages (March 2016) DOI: /j.molcel

Cell-to-Cell Transfer of M. tuberculosis Antigens Optimizes CD4 T Cell Priming Smita Srivastava, Joel D. Ernst Cell Host & Microbe Volume 15, Issue 6,

Merkel Cell Polyomavirus Small T Antigen Controls Viral Replication and Oncoprotein Expression by Targeting the Cellular Ubiquitin Ligase SCFFbw7 Hyun.

Quantitative Single-Cell Approaches to Stem Cell Research Martin Etzrodt, Max Endele, Timm Schroeder Cell Stem Cell Volume 15, Issue 5, Pages (November.

Predicting Vaccine Responsiveness

RAS and ROS—A Story of Pseudomonas Survival

Trained Immunity: An Ancient Way of Remembering

Volume 1, Issue 1, Pages (June 2007)

Influenza A Virus Lures Autophagic Protein LC3 to Budding Sites

Jenner's Irony: Cowpox Taps into T Cell Evasion

Niv Zmora, David Zeevi, Tal Korem, Eran Segal, Eran Elinav

NMD: Nonsense-Mediated Defense

Did Cholera Toxin Finally Get Caught?

Warfare between Host Immunity and Bacterial Weapons

Too Much Sugar Puts a Parasite in Jeopardy

Unsweetened IgG Is Bad for Dengue Patients

Arturo Casadevall, Liise-anne Pirofski Cell Host & Microbe

Volume 18, Issue 4, Pages (October 2015)

Shigella Targets T Cells

Octavio Ramilo, Asunción Mejías Cell Host & Microbe

Where Does Innate Immunity Stop and Adaptive Immunity Begin?

B. Brett Finlay, Grant McFadden Cell

Volume 22, Issue 5, Pages (November 2017)

Claudia Sala, David C. Grainger, Stewart T. Cole Cell Host & Microbe

Commensal Fungi in Health and Disease

Metformin Joins Forces with Microbes

Autophagy, Apoptosis, and the Influenza Virus M2 Protein

A Microbiome Foundation for the Study of Crohn’s Disease

Neutrophils Cause an Intravascular Traffic Jam

Type VI Secretion: Not Just for Pathogenesis Anymore

The CAT(2) Comes Back Cell Host & Microbe

Exploiting Old Pathogens to Create New Therapeutics

At the Intersection of Plant Growth and Immunity

Arturo Casadevall, Liise-anne Pirofski Cell Host & Microbe

Restriction of Zika Virus by Host Innate Immunity

Exploring New Horizons in Microbiome Research

Mycobacterial Lipid Logic

Microbiota and Autoimmunity: Exploring New Avenues

Recognizing Macrophage Activation and Host Defense

Gut Microbes Take Their Vitamins

A Microbiome Foundation for the Study of Crohn’s Disease

The Yeast Saccharomyces cerevisiae: A Versatile Model System for the Identification and Characterization of Bacterial Virulence Proteins Keri A. Siggers,

Yusuke Saijo, Paul Schulze-Lefert Cell Host & Microbe

Wilbert Bitter, Coen Kuijl Cell Host & Microbe

Viral Suppressors of RNA-Based Viral Immunity: Host Targets

Getting a gRIP on Flu by Casting the DAI

Plant TRAF Proteins Regulate NLR Immune Receptor Turnover

Life-Saving Degeneracy in the Human Immune System

Volume 163, Issue 4, (November 2015)

Protectors of the Neonatal Gut: Clostridia Send Pathogens Packing

A Host MicroRNA Brokers Truce with HSV-1

Jenner's Irony: Cowpox Taps into T Cell Evasion

Host and Microbes Date Exclusively

Time Heals All Wounds … But Wounds Heal Faster with Lactobacillus

Mother's Milk and Intrinsic Immunity

Presentation transcript:

Dynamic Intervention: Pathogen Disarmament of Mitochondrial-Based Immune Surveillance Robin L. Holland, Steven R. Blanke Cell Host & Microbe Volume 16, Issue 5, Pages 555-557 (November 2014) DOI: 10.1016/j.chom.2014.10.013 Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 1 Recognition of Pathogens by Host Cell Surveillance (A) Schematic drawing of Vibrio cholerae disarmament of mitochondrial immune surveillance through the T3SS effector VopE resulting in inhibition of mitochondrial perinuclear clustering and immune activation. (B) Models of pathogen recognition by host cell surveillance machinery. PAMP recognition: results in indiscriminate recognition of pathogens and commensals. DAMP recognition: results in time-dependent, indiscriminate response to cell death. Guard hypothesis: results in specific recognition of pathogens and not commensal microbes. Cell Host & Microbe 2014 16, 555-557DOI: (10.1016/j.chom.2014.10.013) Copyright © 2014 Elsevier Inc. Terms and Conditions