Could patient-controlled thirst-driven fluid administration lead to more rapid rehydration than clinician-directed fluid management? An early feasibility.

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Presentation transcript:

Could patient-controlled thirst-driven fluid administration lead to more rapid rehydration than clinician-directed fluid management? An early feasibility study  F. Hughes, S.C. Ng, M. Mythen, H. Montgomery  British Journal of Anaesthesia  Volume 120, Issue 2, Pages 284-290 (February 2018) DOI: 10.1016/j.bja.2017.11.077 Copyright © 2017 British Journal of Anaesthesia Terms and Conditions

Fig 1 A diagram of the movement of participants through our experiment. Participants moved from left to right, passing into either the experimental or control arm, before repeating the protocol in the opposite arm of the trial between 7 and 14 days later. British Journal of Anaesthesia 2018 120, 284-290DOI: (10.1016/j.bja.2017.11.077) Copyright © 2017 British Journal of Anaesthesia Terms and Conditions

Fig 2 Comparison of fluid administration over the 4 h infusion between the experimental arm (green) and control arm (red). (A) Raw data points for each participant. (B) Aggregated plots of the data for all participants. Additionally, the exponential function to which the experimental infusions are fitted is plotted in black. British Journal of Anaesthesia 2018 120, 284-290DOI: (10.1016/j.bja.2017.11.077) Copyright © 2017 British Journal of Anaesthesia Terms and Conditions

Fig 3 Changes in urine specific gravity (left) and thirst score (right) over the course of each infusion. British Journal of Anaesthesia 2018 120, 284-290DOI: (10.1016/j.bja.2017.11.077) Copyright © 2017 British Journal of Anaesthesia Terms and Conditions

Fig 4 Comparison of subjective thirst scores over the 4 h infusion between the experimental arm (green) and control arm (red). (A) Raw data points for each participant. (B) Aggregated plots of the thirst data for all participants. Additionally, the exponential function to which the experimental infusions are fitted is plotted in black. The exponential decrease in thirst in the experimental arm corresponds to the exponential decrease in infusion rate seen in Fig. 2. British Journal of Anaesthesia 2018 120, 284-290DOI: (10.1016/j.bja.2017.11.077) Copyright © 2017 British Journal of Anaesthesia Terms and Conditions

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