Volume 57, Issue 3, Pages (March 2000)

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Volume 57, Issue 3, Pages 875-881 (March 2000) Familial nephrotic syndrome: Clinical spectrum and linkage to chromosome 19q13 Abhay Vats, Alice Nayak, Demetrius Ellis, Parmjeet Singh Randhawa, David N. Finegold, Kara L. Levinson, Robert E. Ferrell Kidney International Volume 57, Issue 3, Pages 875-881 (March 2000) DOI: 10.1046/j.1523-1755.2000.057003875.x Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 1 Children's Hospital of Pittsburg (CHP) family 101 pedigree. The pedigree has been altered to preserve anonymity of the family. The three-digit numbers located under the individual number refer to chromosomal marker used in the study. Symbols are: (□) male; (○) female; (▪) affected; (▪) deceased. Kidney International 2000 57, 875-881DOI: (10.1046/j.1523-1755.2000.057003875.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 2 Spectrum of pathological lesions. (a) A globally sclerotic glomerulus in a biopsy from case II:4 (×700). (b) Focal segmental sclerosis seen in a renal biopsy from patient II:2 (×700). (c) A glomerulus from case III:3 showing focal mesangial proliferation (×350). (d) An essentially normal glomerulus illustrating the histologic appearance classified as minimal change disease (×350). (e) Electron micrograph of III:4 showing extensive foot process fusion. Kidney International 2000 57, 875-881DOI: (10.1046/j.1523-1755.2000.057003875.x) Copyright © 2000 International Society of Nephrology Terms and Conditions