Pioglitazone protects against aging-related renal injury.

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Presentation transcript:

Pioglitazone protects against aging-related renal injury. Pioglitazone protects against aging-related renal injury. Compared with the control group, pioglitazone ameliorated aging-related glomerulosclerosis (scale 0 to 4) and interstitial fibrosis (point counting) (A; paraffin sections, Masson trichrome staining; magnification, ×200) and significantly decreased positive senescence-associated β-galactosidase staining, a senescence marker (B; blue, frozen sections, β-galactosidase staining; magnification, ×100). Hai-Chun Yang et al. JASN 2009;20:2380-2388 ©2009 by American Society of Nephrology