Woo Chi, Odysseas Morgan, Eleanor Wu, Bruce A. Morgan 

Slides:



Advertisements
Similar presentations
Figure S1 a b c d DAPI Lgr β-catenin Merge
Advertisements

Targeted Disruption of the Lama3 Gene in Adult Mice Is Sufficient to Induce Skin Inflammation and Fibrosis  Monika Pesch, Sabrina König, Monique Aumailley 
Julien M. D. Legrand, Edwige Roy, Jonathan J
Transglutaminase 3 Protects against Photodamage
Adenovirus-Mediated Wnt10b Overexpression Induces Hair Follicle Regeneration  Yu-Hong Li, Kun Zhang, Ke Yang, Ji-Xing Ye, Yi-Zhan Xing, Hai-Ying Guo, Fang.
Holocrine Secretion of Sebum Is a Unique DNase2-Dependent Mode of Programmed Cell Death  Heinz Fischer, Judith Fumicz, Heidemarie Rossiter, Markus Napirei,
Kai Kretzschmar, Denny L. Cottle, Pawel J. Schweiger, Fiona M. Watt 
The Thyroid Hormone Analogue KB2115 (Eprotirome) Prolongs Human Hair Growth (Anagen) Ex Vivo  Attila Oláh, Jennifer Gherardini, Marta Bertolini, Jérémy.
Stage-Specific Embryonic Antigen-4 (SSEA-4) as a Distinguishing Marker between Eccrine and Apocrine Origin of Ducts of Sweat Glands  Julia Borowczyk-Michalowska,
Jason E. Hawkes, Johann E. Gudjonsson, Nicole L. Ward 
Transglutaminase 3 Protects against Photodamage
John J. Lemasters, Venkat K. Ramshesh, Gregory L
Transdifferentiation of Melanoma Cells by the Reprogramming Factors Attenuates Malignant Nature In Vitro and In Vivo  Mikiro Takaishi, Shigetoshi Sano 
Identification of Functional Patterns of Androgenetic Alopecia Using Transcriptome Profiling in Distinct Locations of Hair Follicles  Yong Miao, Qian.
In Vivo Detection of Small Subsurface Melanomas in Athymic Mice Using Noninvasive Fiber Optic Confocal Imaging  Peter Anikijenko, Liem T. Vo, Elise R.
Getting to the Core of the Dermal Papilla
Xanthe L. Strudwick, James M. Waters, Allison J. Cowin 
Thiviyani Maruthappu, Lisa A. McGinty, Diana C
Clinical Snippets Journal of Investigative Dermatology
Thomas Yang Sun, Ann M. Haberman, Valentina Greco 
Epidermal Label-Retaining Cells: Background and Recent Applications
Efrat Avigad Laron, Emil Aamar, David Enshell-Seijffers 
Nicole Amberg, Martin Holcmann, Gabriel Stulnig, Maria Sibilia 
Skin-Specific Deletion of Mis18α Impedes Proliferation and Stratification of Epidermal Keratinocytes  Koog Chan Park, Minkyoung Lee, Yoon Jeon, Raok Jeon,
Label-Retaining Cells (Presumptive Stem Cells) of Mice Vibrissae Do Not Express Gap Junction Protein Connexin 43  Maja Matic, Marcia Simon  Journal of.
NF-κB Participates in Mouse Hair Cycle Control and Plays Distinct Roles in the Various Pelage Hair Follicle Types  Karsten Krieger, Sarah E. Millar, Nadine.
Joanne E. Sordillo, Peter Kraft, Ann Chen Wu, Maryam M. Asgari 
TWEAK/Fn14 Signals Mediate Burn Wound Repair
Clinical Snippets Journal of Investigative Dermatology
Murine Vibrissae Cultured in Serum-Free Medium Reinitiate Anagen
Possible Contribution of Fibrocytes to Increased Type I Collagen Synthesis during the Early Stage of Dermal Wound Repair in Human Skin  Min Sun, Peiru.
Mitochondrial Function in Murine Skin Epithelium Is Crucial for Hair Follicle Morphogenesis and Epithelial–Mesenchymal Interactions  Jennifer E. Kloepper,
Gorab Is Required for Dermal Condensate Cells to Respond to Hedgehog Signals during Hair Follicle Morphogenesis  Ying Liu, Elizabeth R. Snedecor, Yeon.
Embryonic Fate Mapping Uncovers the Critical Role of microRNAs in the Development of Epidermal γδ T Cells  Yi Yao, Queping Liu, Carly Martin, Congcong.
Lack of Collagen VI Promotes Wound-Induced Hair Growth
Slc1a3-CreER as a Targeting Tool for the K6+ Epithelial Stem Cell Niche and its Precursors during Mouse Hair Follicle Cycle  Aiko Sada, Prachi Jain, Sherry.
Tamar Nijsten  Journal of Investigative Dermatology 
Francois le Pelletier, Anne Janin  Journal of Investigative Dermatology 
Molecular Mechanisms Regulating Hair Follicle Development
Dissociated Human Dermal Papilla Cells Induce Hair Follicle Neogenesis in Grafted Dermal–Epidermal Composites  Rajesh L. Thangapazham, Peter Klover, Ji-an.
Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation  Grace S. Kaushal, Emanuel Rognoni, Beate M. Lichtenberger,
Journal of Investigative Dermatology
Cancer Stem Cells in Squamous Cell Carcinoma
Clinical Snippets Journal of Investigative Dermatology
Sigrun A.J. Schmidt, Serigne Lo, Loes M. Hollestein 
Research Techniques Made Simple: Itch Measurement in Clinical Trials
Journal of Investigative Dermatology
Wnt Signaling through the β-Catenin Pathway Is Sufficient to Maintain, but Not Restore, Anagen-Phase Characteristics of Dermal Papilla Cells  Hidenao.
Journal of Investigative Dermatology 
Dual-Mode Regulation of Hair Growth Cycle by Two Fgf-5 Gene Products
Michael C. Velarde  Journal of Investigative Dermatology 
Society for Investigative Dermatology 2010 Meeting Minutes
Journal of Investigative Dermatology
sm“FISH”ing for Hedgehog
Erratum Journal of Investigative Dermatology
Colin A.B. Jahoda, Adam C. Gilmore 
Research Snippets Journal of Investigative Dermatology
A Potential Suppressor of TGF-β Delays Catagen Progression in Hair Follicles  Yumiko Tsuji, Sumiko Denda, Tsutomu Soma, Laurel Raftery, Takashi Momoi,
BJD Editor’s Choice Journal of Investigative Dermatology
Thrombospondin-1 Plays a Critical Role in the Induction of Hair Follicle Involution and Vascular Regression During the Catagen Phase  Kiichiro Yano, Michael.
MHC Class I Expression in Murine Skin: Developmentally Controlled and Strikingly Restricted Intraepithelial Expression During Hair Follicle Morphogenesis.
Cells to Surgery Quiz: February 2019
Journal of Investigative Dermatology
Journal of Investigative Dermatology
On the Regulation of Hair Keratin Expression: Lessons from Studies in Pilomatricomas  Bernard Cribier, Bernard Peltre, Edouard Grosshans, Lutz Langbein,
Journal of Investigative Dermatology
Liren Tang, Shabnam Madani, Harvey Lui, Jerry Shapiro 
Journal of Investigative Dermatology
The “Skinny” on Wnt Signaling in Stem Cells
Rolf Hoffmann, Shiro Niiyama  Journal of Investigative Dermatology 
Presentation transcript:

Stabilization of β-Catenin Does Not Increase Dermal Papilla Cell Number in the Hair Follicle  Woo Chi, Odysseas Morgan, Eleanor Wu, Bruce A. Morgan  Journal of Investigative Dermatology  Volume 137, Issue 1, Pages 245-246 (January 2017) DOI: 10.1016/j.jid.2016.08.014 Copyright © 2016 The Authors Terms and Conditions

Figure 1 Dermal papilla (DP) cell number is unchanged in mice with β-catenin stabilized in the DP. (a) Consecutive optical sections through a zigzag hair follicle. DP cells are green, and nuclei are red. (b, c) Magnified image from (a) with (b) and without (c) the green channel to count nuclei in the DP (dotted line, c). (d) DP number per zigzag follicle shown for 4 control mice (Control, red) and 4 mice with β-catenin activated in the DP (CatnEx3, purple). Averages ± standard deviation are shown. (e) Frequency of each hair type in the second hair coat of control mice (red) and mice with β-catenin activated in the DP (CatnEx3, purple). Averages ± standard deviation are shown (n = 13 control mice, n = 12 CatnEx3 mice, at least 250 hairs per mouse analyzed). Scale bar: 25 μm. Journal of Investigative Dermatology 2017 137, 245-246DOI: (10.1016/j.jid.2016.08.014) Copyright © 2016 The Authors Terms and Conditions