A SYSTEM AND DEVICE FOR FOCAL tDCS: HIGH–DEFINITION(HD) tDCS Abhishek Datta Jeff Borckardt, Mark George, Mar Cortes, Dylan Edwards, Felipe Fregni, Eric.

Slides:

Advertisements

Similar presentations

Image Selection T1 and T1 phantom images based on colin27 are used Segmentation Segmentation was performed using BrainSuite Finite Element Mesh Generation.

Advertisements

Prefrontal Cortex transcranial Direct Current Stimulation via a Combined High Definition and Conventional Electrode Montage: A FEM modeling study Dennis.

EE 4BD4 Lecture 20 Therapeutic Stimulation 1. 2 Weak and Strong Stimulation Recording Amplifier AC Coupled (bad choice) 3.

BRAIN PLASTICITY AFTER SPINAL CORD INJURY CORTICAL REORGANIZATION AFTER CHRONIC SCI Mar Cortes Non-invasive Brain Stimulation and Human Motor Control Lab.

C LINICAL S TAFF T RAINING P RESENTATION 1 Crystal Blais, Ph.D. Scientific Affairs Liaison Training Program Manager © 2014 Nuraleve, Inc. Proprietary and.

TMS-evoked EEG responses in symptomatic and recovered patients with mild traumatic brain injury Jussi Tallus 1, Pantelis Lioumis 2, Heikki Hämäläinen 3,

Inducing and Measuring Brain Plasticity Associated with Aphasia Treatment Julius Fridriksson, Ph.D. Department of Communication Sciences & Disorders Arnold.

Scientific Evidence for New Technologies. Audience Scientific Evidence for New Technologies 2 Clinicians Scientist s Engineer s Others.

Brain-computer interfaces: classifying imaginary movements and effects of tDCS Iulia Comşa MRes Computational Neuroscience and Cognitive Robotics Supervisors:

Modulating pain in CRPS with tDCS Giridhar Gundu, M.D. PGY IV Co-investigator: Kenneth Chelette, M.S. Dept. of PM&R University of Kentucky 5/23/2013.

CORTICAL STIMULATION IN APHASIA Richard L. Harvey, MD Rehabilitation Institute of Chicago, Chicago, USA Northwestern University, Feinberg School of Medicine,

Spinal transcutaneous direct current stimulation to enhance locomotor training after spinal cord injury Radha Korupolu, MBBS, MS (pgy2) Physical Medicine.

Presented by: Vanessa Wong Corbetta et al..  Inability to pay attention to space  Most common cause is stroke  Caused by focal injury to temporoparietal.

Noninvasive brain stimulation in neurorehabilitation

Foc.us Alex Simon Biotech Journal Club June 12 th, 2014.

Four Main Approaches Experimental cognitive psychology Cognitive neuropsychology Computational cognitive science Cognitive neuroscience.

Transcranial Magnetic Stimulation

Is motor learning mediated by tDCS intensity? J. F. Daphnie Leenus 1,2, Koen Cuypers 1-3, Femke E. van den Berg 3, Michael A. Nitsche 4, Herbert Thijs.

Stimulating the Brain in Epilepsy

Electrical stimulation of the brain: Deep Brain Stimulation (DBS)

Mild TBI causes a long-lasting elevation of the transcranial magnetic stimulation (TMS) motor threshold Jussi Tallus 1, Pantelis Lioumis 2, Heikki Hämäläinen.

Transcranial Magnetic Stimulation

Transcranial Magnetic Stimulation

PERIPHERAL NERVE FIELD STIMULATION: MIRAGE OR REALITY? Dr Paul Verrills Interventional Pain Physician MBBS FAFMM MPainMed FIPP Metro Spinal Clinic, Australia.

Michael P. Kilgard Healing the Human Brain: The Next Medical Revolution University of Texas at Dallas.

Coffee?. Adderall? Cocaine?

1 Transcranial Direct Current Stimulation Chris Rorden Method Designs Safety.

Brain Research Methods Maddie Coates. Direct Brain Stimulation Direct brain stimulation is when a device is sends a weak electrical current to disrupt.

Marom Bikson Lucas Parra, Dennis Truong, Abhishek Datta, Davide Reato, Asif Rahman, Belen Lafon, Thomas Radman, Jacek Dmochowski, Preet Minhas, Yu Huang,

Effects of DC Electric Field on Synaptic Plasticity and Epileptiform Activities in Thalamocingulate circuitry Effects of DC Electric Field on Synaptic.

Brain NeuroModulation for Stroke W

ELECTRODES FOR RECEPTION AND STIMULATION IN THE BODY.

Methods and Tools for Studying the Brain. Early Methods Lobotomies and Shock Therapy …………

By Brett Kotowski BME Section 2 Presentation 1.  Neurotechnology  Neurotechnology is the use of engineering applications to scan, alter or enhance the.

Cortical Stimulation Improves Skilled Forelimb Use Following a Focal Ischemic Infarct in the Rat Campbell Teskey et al, 2003.

Scott Midavaine, OTR Swedish Medical Center.  Discuss how use of technology combined with functional tasks can improve outcomes  Benefits of Neuroprosthesis.

Modulating seizure-permissive states with weak electric fields Marom Bikson Davide Reato, Thomas Radman, Lucas Parra Neural Engineering Laboratory - Department.

A media webinar co-hosted by the Science Media Centre of Canada Brain stimulation therapies for mental illness.

Brain Research Methods.

Transcranial Magnetic Stimulation (TMS)

Copyright 2004 © Mattioli Engineering All rights reserved Transdermal Delivery Technology.

Alternative Neuroimaging Techniques PET TMS SPECT EEG

AP PSYCHOLOGY: UNIT II Introductory Psychology: Biological Bases of Behavior Topic: Research Methods.

Noninvasive Brain Stimulation in the Investigation and Treatment of Neglect Roy Hamilton, MD, MS Laboratory for Cognition and Neural Stimulation University.

Laboratory for Magnetic Brain Stimulation Felipe Fregni, MD, PhD Assistant Professor Harvard Medical School Neuromodulation for chronic pain.

USING THERAPEUTIC MODALITIES Electrotherapy. ELECTROTHERAPY Electrical current String of electrons that pass along a conductor Intensity of current =

Transcranial Direct Current Stimulation (tDCS ) Direct current stimulation (DCs) is a simple, noninvasive technique for brain stimulation that induces.

Computational Needs for the Growing Field of Neural Engineering Bryan Howell PhD Candidate in Biomedical Engineering CIEMAS 1133 August 27 th,

1 Psychology 304: Brain and Behaviour Lecture 4. 2 Research Methods and The Structure of the Nervous System 2. What are the primary divisions of the nervous.

Treatment of auditory verbal hallucinations in schizophrenia using tDCS Charlotte Chaze 1, Vince P. Clark 1,2, Jessica Turner 1,3, Rose Bigelow 2, Jason.

Date of download: 6/23/2016 Copyright © 2016 SPIE. All rights reserved. (a) This image shows the fNIRS sources (dark blue filled circles), detectors (light.

Biology and Behavior Neuroscience  Scientific study of the brain and of the links between brain activity and behavior.

Transcranial electrical stimulation - tDCS and friends MA Nitsche Georg-August-University, Dept. Clinical Neurophysiology, Goettingen, Germany.

Objective Background Results Conclusions Research supported by The Lourie Center, Inc. The remotely supervised methods proved to be an effective and well-tolerated.

Quantification of Dose with Neuromodulation Device

Does longitudinal frontoparietal tDCS enhance WM in older adults?

DBP: SIMULATION OF DEEP BRAIN STIMULATION

Transcranial direct current stimulation (tDCS) in therapy-resistant depression: Preliminary results from a double-blind, placebo-controlled study. U. Palm,

Developing Homogeneous Current Density Electrode Technology for Transcranial Direct Current Stimulation (tDCS) AsMA May, 2015 R. Andy McKinley1 Mike Resor2.

Pergolide Increases the Efficacy of Cathodal Direct Current Stimulation to Reduce the Amplitude of Laser-Evoked Potentials in Humans Daniella Terney,

Georg-August-University, Dept. Clinical Neurophysiology

تحریک الکتریکی فراجمجمه ای و فعالیت های عصب-شناختی

INOVATE-HF Trial design: Patients with heart failure (HF) were randomized to device implant for vagus nerve stimulation (n = 436) versus optimal medical.

دکتر سید عطاالله عقیلیان روانپزشک شهریور 94

Volume 26, Issue 14, Pages (July 2016)

Pergolide Increases the Efficacy of Cathodal Direct Current Stimulation to Reduce the Amplitude of Laser-Evoked Potentials in Humans Daniella Terney,

Noninvasive Neuromodulation Goes Deep

Intensity Dependent Effects of Transcranial Direct Current Stimulation on Corticospinal Excitability in Chronic Spinal Cord Injury Lynda M. Murray, PhD,

Beth L. Parkin, Hamed Ekhtiari, Vincent F. Walsh Neuron

Variability in sensation intensity due to changes in impedance during electrotactile stimulation. Variability in sensation intensity due to changes in.

Presentation transcript:

A SYSTEM AND DEVICE FOR FOCAL tDCS: HIGH–DEFINITION(HD) tDCS Abhishek Datta Jeff Borckardt, Mark George, Mar Cortes, Dylan Edwards, Felipe Fregni, Eric Wassermann, Marom Bikson Neural Engineering Laboratory - Department of Biomedical Engineering The City College of New York of CUNY Neuromodulation Laboratory, Spaulding Rehabilatation Hospital Harvard Medical School

-application of currents delivered through the scalp to modulate brain activity. TRANSCRANIAL DIRECT CURRENT STIMULATION (tDCS) -number of disorders, rehabilatation and cognitive enhancement -safe,easy to apply, CHEAP!

SPATIAL TARGETING Brain Stimulation Electrodes Current flow and brain modulation Conventional Sponge-based Transcranial DC Stimulation

SPATIAL TARGETING Brain Stimulation Electrodes Current flow and brain modulation High-Definition (HD) Transcranial DC Stimulation Ring Configuration

High-definition (HD) Transcanial (4x1 Ring) Conventional Transcanial (large pad) FEM ANALYSIS OF TRANSCRANIAL ELECTROTHERAPY FOCALITY

CONVENTIONAL tDCS

Min Max Electric field 1 mA Datta et al., 2009 CONVENTIONAL tDCS

HIGH DEFINITION (HD)- tDCS

Min Max Electric field 2 mA HIGH DEFINITION (HD)- tDCS Datta et al., 2009

HD tDCS – 4x1 Hardware DevelopmentClinical Trials NIH-NINDS Eric Wassermann, Egas Caparelli Dáquer MUSC Mark George Jeff Borckardt Burke Rehabilitation Dylan Edwards Mar Cortes Harvard (Spaulding) Felipe Fregni ……. Soterix Medical

PILOT CLINICAL STUDY 1: EXPERIMENTAL PAIN (MUSC) Setup

PILOT CLINICAL STUDY 1: EXPERIMENTAL PAIN (MUSC) Borckardt et al., under review Analgesic effects in an experimental pain model…… Significant effect for sensory thresholds.

Edwards et al., under review Targeting Validation PILOT CLINICAL STUDY 2: COMBINED TES & MODELING (BURKE REHABILATATION) Transcranial Electrical Stimulation (TES) – short high-intensity pulse that triggers motor response (MEP)

ANODE:C3 CATHODE:FC5,FC1,CP5,CP1 PILOT CLINICAL STUDY 2: COMBINED TES & MODELING (BURKE REHABILATATION) ANODE:F3 CATHODE:AF7,AFz,FC5,FC1 ANODE:P3 CATHODE:CP5,CP1,PO7,POz Peak 0 Electric field/Current density 33% 66% Edwards et al., under review

-Retains advantages of conventional therapy ADVANTAGE OF HD CONFIGURATIONS: Other configurations can be used: (4 X 4, 5X2…) based on application -Cortical regions can be selectively targeted using a HD system. -Customizable (individualized therapy) Procedures, implants… Skull Defects / TBI Stroke