Liver is liver and blood is blood, and finally the twain have met Karl-Dimiter Bissig, Silke Paust, Mercedes Barzi Journal of Hepatology Volume 65, Issue 2, Pages 245-248 (August 2016) DOI: 10.1016/j.jhep.2016.05.018 Copyright © 2016 European Association for the Study of the Liver Terms and Conditions
Fig. 1 Liver and hematopoietic dual chimeric mouse models. Both the liver and the hematopoietic system have been repopulated in six different chimeric mouse models. The possible and actual cell sources, applications and areas for future improvement are listed. EBV, Epstein Barr virus; ESC, embryonic stem cell; CMV, cytomegalovirus; DILI, drug induced liver injury; G-CSF, granulocyte colony stimulating factor; GvH, graft vs. host; HBV, hepatitis B virus; HCV, hepatitis C virus; HIV, human immunodeficiency virus; HLA, human leucocyte antigen; HSC, hematopoietic stem cells; iPSC, induced pluripotent stem cell. Journal of Hepatology 2016 65, 245-248DOI: (10.1016/j.jhep.2016.05.018) Copyright © 2016 European Association for the Study of the Liver Terms and Conditions