It’s a SMAD/SMAD World Cell

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It’s a SMAD/SMAD World Cell Cullen Taniguchi, Anirban Maitra Cell Volume 161, Issue 6, Pages 1245-1246 (June 2015) DOI: 10.1016/j.cell.2015.05.030 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Runx3 Could Improve the Utility of Smad4 as a Biomarker of Pancreatic Cancer Biology Patients with the combination of detectable Smad4 expression and a low level of Runx3 may benefit from aggressive local therapy because of the proliferative nature of the tumors. In contrast, tumors with undetectable Smad4 or a high level of Runx3 tend to be highly metastatic, and the therapeutic regime should be tailored accordingly. Cell 2015 161, 1245-1246DOI: (10.1016/j.cell.2015.05.030) Copyright © 2015 Elsevier Inc. Terms and Conditions