Phase III Trial Comparing Paclitaxel Poliglumex (CT-2103, PPX) in Combination with Carboplatin Versus Standard Paclitaxel and Carboplatin in the Treatment.

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Presentation transcript:

Phase III Trial Comparing Paclitaxel Poliglumex (CT-2103, PPX) in Combination with Carboplatin Versus Standard Paclitaxel and Carboplatin in the Treatment of PS 2 Patients with Chemotherapy-Naïve Advanced Non-small Cell Lung Cancer Corey J. Langer, MD, FACP, Kenneth J. O’Byrne, MD, Mark A. Socinski, MD, Sergei M. Mikhailov, MD, Krzysztof Leśniewski-Kmak, MD, Martin Smakal, MD, Tudor E. Ciuleanu, MD, Sergey V. Orlov, MD, Mircea Dediu, MD, PhD, David Heigener, MD, Amy J. Eisenfeld, PhD, Larissa Sandalic, MS, Fred B. Oldham, MD, Jack W. Singer, MD, Helen J. Ross, MD Journal of Thoracic Oncology Volume 3, Issue 6, Pages 623-630 (June 2008) DOI: 10.1097/JTO.0b013e3181753b4b Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Overall survival using Kaplan-Meier estimation. (A) Paclitaxel poliglumex/carboplatin versus paclitaxel/carboplatin. (B) Paclitaxel/carboplatin—United States/Western Europe/Canada versus Eastern Europe. (C) PPX/carboplatin—United States/Western Europe/Canada versus Eastern Europe. Journal of Thoracic Oncology 2008 3, 623-630DOI: (10.1097/JTO.0b013e3181753b4b) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions