A Long-Term Spinal Intramedullary Response to Ceritinib in ALK Rearranged Non– Small-Cell Lung Cancer  Josette Biya, MD, Caroline Caramella, MD, Colin.

Slides:



Advertisements
Similar presentations
Choroidal Metastases Responsive to Crizotinib Therapy in a Lung Adenocarcinoma Patient with ALK 2p23 Fusion Identified by ALK Immunohistochemistry Yan.
Advertisements

Massive Bronchogenic Cyst Joseph B. Levin, BA, Chi Wan Koo, MD, Jessica S. Donington, MD Journal of Thoracic Oncology Volume 5, Issue 11, Pages
Development of Renal Cysts after Crizotinib Treatment in Advanced ALK-Positive Non– Small-Cell Lung Cancer Yen-Ting Lin, MD, Yu-Fen Wang, MD, James Chih-Hsin.
Carcinoma NOS is a Common Histologic Diagnosis and is Increasing in Proportion Among Non-small Cell Lung Cancer Histologies  Sai-Hong Ignatius Ou, MD,
Two Classic Lyrics Joined by a Contemporary Tune—Environmental Pro-Carcinogen Exposure and Genetic Susceptibility in Lung Cancer Risk  Ping Yang, MD,
Brain Radionecrosis Treated with Bevacizumab in a Patient with Resected Squamous Cell Carcinoma of the Lung  Jordi Remon, MD, Cécile Le Péchoux, MD, Caroline.
Intramedullary Spinal Cord Hemorrhage after Treatment with Bevacizumab in a Long- term Survivor with Metastatic Non–Small-Cell Lung Cancer  Kristin N.
Hironori Yoshida, MD, Young Hak Kim, MD  Journal of Thoracic Oncology 
Disparities in Treatment of Patients with Inoperable Stage I Non–Small Cell Lung Cancer: A Population-Based Analysis  Matthew Koshy, MD, Renuka Malik,
Leptomeningeal and Medullary Response to Second-Line Erlotinib in Lung Adenocarcinoma  Mathilde Wagner, MD, Benjamin Besse, MD, Corinne Balleyguier, MD,
ALK FISH and IHC: You Cannot Have One without the Other
Durable Response to Tyrosine Kinase Inhibitor Therapy in a Lung Cancer Patient Harboring Epidermal Growth Factor Receptor Tandem Kinase Domain Duplication 
Response to Crizotinib Rechallenge after Initial Progression and Intervening Chemotherapy in ALK Lung Cancer  Eiko Theodora Browning, MD, Andrew James.
Identification of a Novel ALK G1123S Mutation in a Patient with ALK-rearranged Non– small-cell Lung Cancer Exhibiting Resistance to Ceritinib  Gouji Toyokawa,
NA  Journal of Thoracic Oncology 
Electronic Updates for JTO Readers
Rapid Response of Brain Metastasis to Crizotinib in a Patient with ALK Rearrangement– Positive Non–Small-Cell Lung Cancer  Hiroyasu Kaneda, MD, PhD, Isamu.
A Case of Large-Cell Neuroendocrine Carcinoma Harboring an EML4–ALK Rearrangement with Resistance to the ALK Inhibitor Crizotinib  Naoki Omachi, MD, Shigeki.
Hironori Yoshida, MD, Young Hak Kim, MD  Journal of Thoracic Oncology 
The International Association for the Study of Lung Cancer International Staging Project on Lung Cancer  Peter Goldstraw, MB, FRCS, John J. Crowley, PhD 
Effect of Chemotherapy in Patients With Resected Small-Cell or Large-Cell Neuroendocrine Carcinoma  Nader Abedallaa, MD, Lise Tremblay, MD, Charlotte.
Central versus Peripheral Tumor Location: Influence on Survival, Local Control, and Toxicity Following Stereotactic Body Radiotherapy for Primary Non–Small-Cell.
Bilateral Patellar Metastases from Non-small Cell Lung Cancer
The Influence of the Evolution of First-Line Chemotherapy on Steadily Improving Survival in Advanced Non-Small-Cell Lung Cancer Clinical Trials  Krista.
A Severe Photosensitivity Dermatitis Caused by Crizotinib
The Central Nervous System as a Sanctuary Site in ALK-Positive Non–Small-Cell Lung Cancer  Justin F. Gainor, MD, Sai-Hong Ignatius Ou, MD, PhD, Jennifer.
CSF Concentration of Crizotinib in Two ALK-Positive Non–Small-Cell Lung Cancer Patients with CNS Metastases Deriving Clinical Benefit from Treatment 
Intratumoral Lymphatic Vessel Involvement is an Invasive Indicator of Completely Resected Pathologic Stage I Non-small Cell Lung Cancer  Masahiko Harada,
Effects of Chemotherapy on Survival of Elderly Patients with Small-Cell Lung Cancer: Analysis of the SEER-Medicare Database  Laura C. Caprario, MD, MS,
Crizotinib Improves Osteoarthritis Symptoms in a ROS1-Fusion Advanced Non–Small Cell Lung Cancer Patient  Jordi Remon, MD, Anas Gazzah, MD, Benjamin Besse,
Bilateral Subdural Hematoma Associated with Central Nervous System Metastases from Lung Cancer  Akito Hata, MD, Shiro Fujita, MD, PhD, Nobuyuki Katakami,
Socioeconomic Status Is Associated with Depressive Severity Among Patients with Advanced Non–Small-Cell Lung Cancer: Treatment Setting and Minority Status.
In This Issue Journal of Thoracic Oncology
Jeffrey T. Yorio, MD, Yang Xie, PhD, Jingsheng Yan, PhD, David E
Do Complex Mutations of the Epidermal Growth Factor Receptor Gene Reflect Intratumoral Heterogeneity?  Akito Hata, MD, Shiro Fujita, MD, PhD, Reiko Kaji,
Ineffectiveness of Crizotinib on Brain Metastases in Two Cases of Lung Adenocarcinoma with EML4-ALK Rearrangement  Denis Maillet, MD, Isabelle Martel-Lafay,
Nivolumab-Induced Acute Diabetes Mellitus and Hypophysitis in a Patient with Advanced Pulmonary Pleomorphic Carcinoma with a Prolonged Tumor Response 
Elizabeth Cathcart-Rake, MD, Ariel Lopez-Chavez, MD, MS 
Vamsidhar Velcheti, MD  Journal of Thoracic Oncology 
ALK Translocation in Non-small Cell Lung Cancer with Adenocarcinoma and Squamous Cell Carcinoma Markers  Samuel J. Klempner, MD, David W. Cohen, MD, Daniel.
Mitotic Inhibitors Journal of Thoracic Oncology
Mirror Mirror on the Wall, Who Is the Fairest of Them All
EGFR delE709_T710insD: A Rare but Potentially EGFR Inhibitor Responsive Mutation in Non–Small-Cell Lung Cancer  Allison Ackerman, MD, Michael A. Goldstein,
Trends in Stage Distribution for Patients with Non-small Cell Lung Cancer: A National Cancer Database Survey  Daniel Morgensztern, MD, Shean Huey Ng,
An IRIS to Remember The American Journal of Medicine
Atypical Negative ALK Break-Apart FISH Harboring a Crizotinib-Responsive ALK Rearrangement in Non–Small-Cell Lung Cancer  Shengxiang Ren, MD, PhD, Fred.
Pulmonary Metastasectomy in Breast Cancer
MET 14 Deletion in Sarcomatoid Non-Small-Cell Lung Cancer Detected by Next- Generation Sequencing and Successfully Treated with a MET Inhibitor  Carrie.
Phase I Study of Lenalidomide in Solid Tumors
T4 or MI? Journal of Thoracic Oncology Volume 6, Issue 3, (March 2011)
Jie Huang, Juan Peng, Linlang Guo, MD, PhD 
Recursive Partitioning Analysis Groups II–III Brain Metastases of Non-small Cell Lung Cancer: A Phase II Randomized Study Comparing Two Concurrent Chemoradiotherapy.
Manoj P. Menon, MD, MPH, Keith D. Eaton, MD, PhD 
In This Issue Journal of Thoracic Oncology
Genetic Changes in Squamous Cell Lung Cancer: A Review
Marianna Koczywas, MD, Mihaela C. Cristea, MD 
Ethnic Differences in the Management of Lung Cancer in New Zealand
European Lung Cancer Conference (ELCC) 2016 Organisation
S-1 Treatment for Chemorefractory Thymic Carcinoma
IASLC 6th Latin American Conference on Lung Cancer
Christina S. Baik, MD, MPH, Marc C. Chamberlain, MD, Laura Q. Chow, MD 
Tumor Lysis Syndrome in Limited-Stage Small-Cell Lung Cancer
David Garfield, MD  Journal of Thoracic Oncology 
Alectinib Dose Escalation Reinduces Central Nervous System Responses in Patients with Anaplastic Lymphoma Kinase–Positive Non–Small Cell Lung Cancer Relapsing.
ALK Gene Rearrangements: A New Therapeutic Target in a Molecularly Defined Subset of Non-small Cell Lung Cancer  Benjamin Solomon, MBBS, PhD, Marileila.
A Review of First-Line Treatment for Small-cell Lung Cancer
Mark A. Socinski, MD  Journal of Thoracic Oncology 
Miliary Brain Metastases in a Patient with ROS1-Rearranged Lung Adenocarcinoma: A Case Report  Katarzyna Dziadziuszko, MD, Edyta Szurowska, MD, PhD, Joanna.
Robert Comis, MD, The Passing of a “Lung Man”
Ana Luque, MD, Edurne Arriola, MD, PhD  Journal of Thoracic Oncology 
Presentation transcript:

A Long-Term Spinal Intramedullary Response to Ceritinib in ALK Rearranged Non– Small-Cell Lung Cancer  Josette Biya, MD, Caroline Caramella, MD, Colin R. Lindsay, MD, David Planchard, MD, PhD, Benjamin Besse, MD, PhD  Journal of Thoracic Oncology  Volume 10, Issue 6, Pages e44-e45 (June 2015) DOI: 10.1097/JTO.0000000000000501 Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Magnetic resonance imaging of T1-enhanced sequence in sagittal axis (A) before and (B) after 2 months of LDK378 (arrows). Journal of Thoracic Oncology 2015 10, e44-e45DOI: (10.1097/JTO.0000000000000501) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions