Dong Feng1 et al. Acta Pharmacol Sin 2015; 36: 1462–1472;

Slides:



Advertisements
Similar presentations
Let’s Talk About Cholesterol Emily Lundstrom, R.Ph., Pharm.D. Melissa Kalb, RD, LD August 8, 2007.
Advertisements

Women and Cholesterol What You Need to Know. Age: 45 Women and Cholesterol: What You Need to Know HDL: 60 mg/dL and above LDL: Below 100 mg/dL GoodBad.
© 2003, Wellsource Inc. Effect of Ketogenic Diet on Lipid Levels (shown is LDL-C) In this group of 141 children followed for 6 months, a ketogenic diet.
The FATZO mouse as a Translational Model for the Development of Drugs for Obesity, Metabolic Syndrome and Diabetes. PreClinOmics, Inc. 1.
Parameters BD PP CP TC (mg. dl-l) ± * ± 5.8
Dufaux, International Journal of Sports Medicine, 1982 TRIGLYCERIDES & TRAINING Increase Decrease No Change Numbers of Studies.
Effect of fish oil supplementation on serum triglycerides, LDL cholesterol and LDL subfractions in hypertriglyceridemic adults  B. Oelrich, A. Dewell,
Supplemental Figure 1 A B C D E F
Krill oil supplementation lowers serum triglycerides without increasing low-density lipoprotein cholesterol in adults with borderline high or high triglyceride.
Steamed black soybeans
Fig. 1. Serum total cholesterol (A), LDL cholesterol (B), triglyceride (C) and HDL cholesterol level (D) according to HBsAg status in age group. Total.
Chen Yali;Yin Mengmei;Cao Xuejin;Hu Gang;Xiao Ming;
© The Author(s) Published by Science and Education Publishing.
Statistical colorings of 1H NMR estimates of biochemical variables.
Arterioscler Thromb Vasc Biol
Effects of High Density Lipoprotein Raising Therapies on Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus, with or without Renal Impairment:
Figure 7 Mendelian randomization of overlapping exposures
برنامه راهبردی پیشگیری و کنترل بیماری های قلبی عروقی
Hypoglycemic and hypolipidemic effect and antioxidant activity of chronic epigallocatechin-gallate in streptozotocin-diabetic rats  Mehrdad Roghani, Tourandokht.
Simple Cysts in Donor Kidney Contribute to Reduced Allograft Function
Wei Shi et al. Acta Pharmacol Sin 2013; 34: 342–351;
Alligator pepper/Grain of Paradise (Aframomum melegueta) modulates Angiotensin-I converting enzyme activity, lipid profile and oxidative imbalances in.
Fig. 3. Fc fusion GDF15 molecules improve metabolic parameters in obese mice and obese cynomolgus monkeys. Fc fusion GDF15 molecules improve metabolic.
different predicted values (D)
low-sedentary control group (LHS)
Fig. 2. Effects of SFN in mouse hepatocytes and in rat models of diet-induced glucose intolerance. Effects of SFN in mouse hepatocytes and in rat models.
Rats (open cycle), HFD rats (open triangle) and DM rats (solid cycle)
Volume 9, Issue 3, Pages (May 2003)
Subject Characteristics
Hajer GR et al. Atherosclerosis 2009;202:216-24
Classification of statins/dosages according to the attainable
Radiological findings on the development of ossification of the posterior longitudinal ligament (OPLL)-like ectopic ossification in famotidine-treated.
Fig. 7. Therapeutic effects of hiPSC-EPO protein on renal anemia in adenine-treated mice. Therapeutic effects of hiPSC-EPO protein on renal anemia in adenine-treated.
The preventive role of TR in HFD‐treated mice
Dan-dan Tian1, 2 et al. Acta Pharmacol Sin 2015; 36: 627–643;
High‐fat diet augments gut permeability, metabolic endotoxemia, and systemic inflammation High‐fat diet augments gut permeability, metabolic endotoxemia,
(A) Low-density lipoprotein-cholesterol (LDL-C) values at baseline and after treatment with anagliptin in 20 participants at 12 and 24 weeks. (A) Low-density.
Change in (A) total cholesterol; (B) LDL-cholesterol; (C) HDL-cholesterol and (D) triglycerides over 5 years in response to 12-week intensive lifestyle.
Therapeutic role of TR in HFD‐established diabetic mice
Chronic effect of 28-day oral administration of vehicle (n = 6–10/group) or aprocitentan 1, 10, and 100 mg/kg per day (n = 6–9/group) on mean arterial.
Effect of 11-day oral administration of vehicle (n = 4) or 6-day oral administration of enalapril 10 mg/kg per day (n = 19), followed by 5-day oral administration.
CNP520 treatment of male C57/BL6 mice for 8 weeks did not cause hair depigmentation CNP520 treatment of male C57/BL6 mice for 8 weeks did not cause hair.
Dan-dan Tian1, 2 et al. Acta Pharmacol Sin 2015; 36: 627–643;
Systemic GADD45β deletion affects metabolic regulation under conditions of heightened lipid metabolism Systemic GADD45β deletion affects metabolic regulation.
Azithromycin treatment eliminates NTHi infection.
Effects of tumour size on response to treatment in the KPC model.
(A) Plasma renin activity in Wistar rats, SHRs, and DOCA-salt rats, n = 8 to 9/group; data are presented as mean ± S.E.M. Dose-response relationship on.
Percentage of patients with type 2 diabetes with A1C < 7% (n = 248), blood pressure > 130/80 mmHg (n = 248), and LDL cholesterol < 100 mg/dl (n = 207)
Oral administration of CX-4945 suppresses Tau phosphorylation in DYRK1A-overexpressing mice. Oral administration of CX-4945 suppresses Tau phosphorylation.
Effect of high-fat (breeder food) diet and 16 h of fasting on triglyceride levels and leptin transport. Effect of high-fat (breeder food) diet and 16 h.
Correlation between progranulin (dependent variable) and CKD stage adjusted for age and sex, as well as DBP, WHR, triglycerides, HDL cholesterol, LDL cholesterol,
Chen Cheng1 et al. Acta Pharmacol Sin 2013; 34: 1337–1348;
diabetic rats treated with BPHs
DPP4 release of explants obtained from adipose tissue of lean controls and obese patients before and after bariatric surgery, and linear correlation with.
Effects of pterosin A on serum levels of lipid, blood urea nitrogen (BUN), creatinine, aspartate aminotransferase (AST), and alanine aminotransferase (ALT)
A: Chemical structure of pterosin A
Fig. 5. Serum estrogen concentration in rats following different treatments. 24 female Sprague–Dawley rats with ovariectomy underwent intraperitoneal administration.
Treatment of high-fat diet–fed mice with TTR-ASOs decreases circulating TTR and RBP4 levels, and improves insulin sensitivity. Treatment of high-fat diet–fed.
Effects of Rosi treatment on ASKO mice.
Decreased M1 and increased M2 macrophages in eWAT and liver of DIO mice due to linagliptin administration. Decreased M1 and increased M2 macrophages in.
Effects of rhein on FBG (A) and glucose intolerance (B) in db/db mice.
Individual lipid measures for high-carbohydrate (n=10) and low-carbohydrate (n=10) ultra-endurance athletes. Individual lipid measures for high-carbohydrate.
© The Author(s) Published by Science and Education Publishing.
Paclitaxel treatment along with CXCR2 knockdown reduces tumor growth and metastasis. Paclitaxel treatment along with CXCR2 knockdown reduces tumor growth.
Mean percentage change from baseline in total IGF-I and the R1507 serum concentration values following a single i.v. administration of R mg/kg (n.
Fig. 1. GDF15 is up-regulated with obesity, and AAV-GDF15 improves metabolic parameters in DIO mice. GDF15 is up-regulated with obesity, and AAV-GDF15.
Recruitment of CD8+, CD4+, and Foxp3+ cells into oral lesions in response to anti–PD-1 treatment. Recruitment of CD8+, CD4+, and Foxp3+ cells into oral.
Changes of major clinical and biochemical characteristics at baseline and during follow-up in different groups. Changes of major clinical and biochemical.
Fig. 3. Effects of SFN in mice with diet-induced diabetes.
Volume 1, Issue 5, Pages (May 2005)
Presentation transcript:

Dong Feng1 et al. Acta Pharmacol Sin 2015; 36: 1462–1472; Figure 1 Quantification of serum cholesterol (total, LDL, HDL) and triglycerides in high fat diet-treated C57BL/6 male mice after oral administration of lovastatin (Lv) 10 mg/kg, Xuezhikang (XZK) 1200 mg/kg, F1(isoflavones) 27.5 mg/kg, F2 (monacolins) 11.3 mg/kg, or F3 (sterols) 35.0 mg/kg for 10 weeks, respectively Figure legends Dong Feng1 et al. Acta Pharmacol Sin 2015; 36: 1462–1472; doi: 10.1038/aps.2015.98 Published by © 2015 CPS and SIMM