Identifying human disease genes Overview Position independent methods Positional cloning Synteny Drosophila mutants that are positional candidates for human disease genes

Identifying human disease genes Overview of the process

Identifying human disease genes Position independent methods Complementation

Identifying human disease genes Position dependent methods CF gene chromosome jumping and walking

Identifying human disease genes Mouse and human synteny

Identifying human disease genes Drosophila and human disorders

Genetic testing Overview Examples CF gene

Genetic testing CF testing ARMs OLA Sequencing Heteroduplex screening DGGE Mismatch cleavage

Genetic testing Oligonucleotide arrays

Genetic testing Forensics Paternity testing Identification