Correlation Does Not Imply Causation: Histone Methyltransferases, but Not Histone Methylation, SET the Stage for Enhancer Activation  Tim Pollex, Eileen.

Slides:



Advertisements
Similar presentations
Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer Shaun K. Olsen, Christopher D. Lima Molecular Cell Volume 49, Issue 5, Pages.
Advertisements

HnRNP L and HnRNP A1 Induce Extended U1 snRNA Interactions with an Exon to Repress Spliceosome Assembly Ni-Ting Chiou, Ganesh Shankarling, Kristen W. Lynch.
Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.
Mechanistic Insight into Site-Restricted Monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI Arno F. Alpi, Paul E. Pace, M. Madan Babu, Ketan J. Patel.
What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity Michael S. Rooney, Sachet A. Shukla, Catherine J. Wu, Gad Getz,
An Ancient Mechanism for Splicing Control: U11 snRNP as an Activator of Alternative Splicing Jens Verbeeren, Elina H. Niemelä, Janne J. Turunen, Cindy.
Conserved Bacterial RNase YbeY Plays Key Roles in 70S Ribosome Quality Control and 16S rRNA Maturation Asha Ivy Jacob, Caroline Köhrer, Bryan William Davies,
Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni
Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet
Cost of Unneeded Proteins in E. coli Is Reduced after Several Generations in Exponential Growth Irit Shachrai, Alon Zaslaver, Uri Alon, Erez Dekel Molecular.
Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell
Distinct Properties of Cell-Type-Specific and Shared Transcription Factor Binding Sites Jason Gertz, Daniel Savic, Katherine E. Varley, E. Christopher.
Telomeric Noncoding RNA TERRA Is Induced by Telomere Shortening to Nucleate Telomerase Molecules at Short Telomeres Emilio Cusanelli, Carmina Angelica.
Mutant K-Ras Activation of the Proapoptotic MST2 Pathway Is Antagonized by Wild- Type K-Ras David Matallanas, David Romano, Fahd Al-Mulla, Eric O'Neill,
Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem
IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.
Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.
Interplay between HDAC3 and WDR5 Is Essential for Hypoxia-Induced Epithelial- Mesenchymal Transition Min-Zu Wu, Ya-Ping Tsai, Muh-Hwa Yang, Chi-Hung Huang,
The Metabolic Basis of Pulmonary Arterial Hypertension Gopinath Sutendra, Evangelos D. Michelakis Cell Metabolism Volume 19, Issue 4, Pages (April.
The BCL-2 Family Reunion Jerry E. Chipuk, Tudor Moldoveanu, Fabien Llambi, Melissa J. Parsons, Douglas R. Green Molecular Cell Volume 37, Issue 3, Pages.
The Mitochondrial Basis of Aging Nuo Sun, Richard J. Youle, Toren Finkel Molecular Cell Volume 61, Issue 5, Pages (March 2016) DOI: /j.molcel
E3-Independent Monoubiquitination of Ubiquitin-Binding Proteins Daniela Hoeller, Christina-Maria Hecker, Sebastian Wagner, Vladimir Rogov, Volker Dötsch,
The Nucleoplasmin Homolog NLP Mediates Centromere Clustering and Anchoring to the Nucleolus Jan Padeken, María José Mendiburo, Sarantis Chlamydas, Hans-Jürgen.
Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel
Quantitative Single-Cell Approaches to Stem Cell Research Martin Etzrodt, Max Endele, Timm Schroeder Cell Stem Cell Volume 15, Issue 5, Pages (November.
Central Dogma Goes Digital
Valeria V. Orlova, Christine L. Mummery  Cell Stem Cell 
Inter-chromosomal Contact Properties in Live-Cell Imaging and in Hi-C
The DNA Damage Response: Ten Years After
Structural Insights into Riboswitch Control of the Biosynthesis of Queuosine, a Modified Nucleotide Found in the Anticodon of tRNA  Mijeong Kang, Robert.
Saving the Ends for Last: The Role of Pol μ in DNA End Joining
Skill Development in Graduate Education
Picky Hsp90—Every Game with Another Mate
How To Choose a Good Scientific Problem
Bringing IDH into the Fold
Jan Philipp Junker, Alexander van Oudenaarden  Molecular Cell 
Volume 46, Issue 5, Pages (June 2012)
Life after MOMP Molecular Cell
Joseph W. Briggs, Jonathan D. Dinman  Molecular Cell 
Decoding Chromatin Goes High Tech
William G. Kaelin, Peter J. Ratcliffe  Molecular Cell 
Eukaryotic Transcription Activation: Right on Target
Joseph W. Briggs, Jonathan D. Dinman  Molecular Cell 
Hijacking the DNA Damage Response to Enhance Viral Replication: γ-Herpesvirus 68 orf36 Phosphorylates Histone H2AX  Anyong Xie, Ralph Scully  Molecular.
MicroRNAs and Viral Infection
A Finer Print Than TADs: PRC1-Mediated Domains
Small Molecules, Big Effects: A Role for Chromatin-Localized Metabolite Biosynthesis in Gene Regulation  Bryan A. Gibson, W. Lee Kraus  Molecular Cell 
Nuclear PI5P, Uhrf1, and the Road Not Taken
Structural Insights into Riboswitch Control of the Biosynthesis of Queuosine, a Modified Nucleotide Found in the Anticodon of tRNA  Mijeong Kang, Robert.
Gourisankar Ghosh, Malini Sen  Molecular Cell 
Epigenetic Control of Autophagy: Nuclear Events Gain More Attention
Volume 36, Issue 2, Pages (October 2009)
Volume 66, Issue 4, Pages e4 (May 2017)
Functional Enhancer Screening in Single Cells
Crossing the Exon Molecular Cell
LOX Out, Histones: A New Enzyme Is Nipping at Your Tails
The Cell Biology of Genomes: Bringing the Double Helix to Life
Eaf3 Chromodomain Interaction with Methylated H3-K36 Links Histone Deacetylation to Pol II Elongation  Amita A. Joshi, Kevin Struhl  Molecular Cell  Volume.
A FIRE-y PAGE in the Computational Analysis of Cancer Profiles
The Plasticity of Aging: Insights from Long-Lived Mutants
How To Survive and Thrive in the Mother-Mentor Marathon
To Infinium, and Beyond! Cancer Cell
The DNA Damage Response: Ten Years After
How To Choose a Good Scientific Problem
Volume 61, Issue 2, Pages (January 2016)
Chaos Controlled: Discovery of a Powerful Amyloid Inhibitor
Volume 25, Issue 2, Pages (January 2007)
Epigenome Sequencing Comes of Age
Gene Regulation in the Postgenomic Era: Technology Takes the Wheel
Presentation transcript:

Correlation Does Not Imply Causation: Histone Methyltransferases, but Not Histone Methylation, SET the Stage for Enhancer Activation  Tim Pollex, Eileen E.M. Furlong  Molecular Cell  Volume 66, Issue 4, Pages 439-441 (May 2017) DOI: 10.1016/j.molcel.2017.05.005 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 Schematic Showing the Key Properties of Enhancers and Their Associated Genes in Different Mll3/Mll4 Mutants WT, wild-type Mll3/4; dKO, double knockout of Mll3/Mll4; dCD, catalytically dead Mll3/Mll4. Molecular Cell 2017 66, 439-441DOI: (10.1016/j.molcel.2017.05.005) Copyright © 2017 Elsevier Inc. Terms and Conditions