#significant difference versus baseline (P<.05). Height SDS Height Velocity (cm/year) Changes in height SDS and height velocity during GH treatment in cystinotic children receiving conservative treatment (CT) (A,B), receiving dialysis (D) (C,D) and after renal transplantation (Tx), (E,F). Patients receiving conservative treatment were subdivided into those who were treated for 1 year ((--) n=45), 2 years ((--) n=30), 3 years ((-- n=19), 4 years ((-- n=11), and 5 years ((-- n=8). Analysis for children receiving conservative treatment was restricted to patients who remained prepubertal during entire observation period. *significant difference versus previous year (P<.01). #significant difference versus baseline (P<.05). C D Height SDS Height Velocity (cm/year) E F Height SDS Height Velocity (cm/year) Abbildung mod. nach Wühl, 2001 rhGH treatment years rhGH treatment years