Treatment of Long-Lasting Persistent Atrial Fibrillation Using Minimally Invasive Surgery Combined With Irbesartan Jian-Gang Wang, MD, Yan Li, MD, Jia-Hai.

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Treatment of Long-Lasting Persistent Atrial Fibrillation Using Minimally Invasive Surgery Combined With Irbesartan Jian-Gang Wang, MD, Yan Li, MD, Jia-Hai Shi, MD, Jie Han, MD, Yong-Qiang Cui, MD, Tian-Ge Luo, MD, Xu Meng, MD The Annals of Thoracic Surgery Volume 91, Issue 4, Pages 1183-1189 (April 2011) DOI: 10.1016/j.athoracsur.2010.11.063 Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Video-assisted thoracoscopic surgical ablation. (A) Right thoracoscopic view of the dry bipolar clamp in place on the left atrial antrum, medial to the right pulmonary vein. (B) The left atrial appendage was excised by stapling it with a surgical stapler. The Annals of Thoracic Surgery 2011 91, 1183-1189DOI: (10.1016/j.athoracsur.2010.11.063) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Comparison of recurrence after atrial fibrillation ablation with irbesartan (group 1 [solid line]) and without irbesartan (group 2 [dotted line]). Kaplan-Meier curve analysis of the incidence of recurrent arrhythmia after ablation in both groups. (CI = confidence interval.) The Annals of Thoracic Surgery 2011 91, 1183-1189DOI: (10.1016/j.athoracsur.2010.11.063) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Comparative use of antiarrhythmic drugs after atrial fibrillation ablation with irbesartan (group 1 [solid line] and without irbesartan (group 2 [dotted line]). Kaplan-Meier curve analysis of the incidence of use of antiarrhythmic drugs after ablation in both groups. The Annals of Thoracic Surgery 2011 91, 1183-1189DOI: (10.1016/j.athoracsur.2010.11.063) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Comparative size of the left atrium with irbesartan (group 1 [blue line]) and without irbesartan (group 2 [red line]). The Annals of Thoracic Surgery 2011 91, 1183-1189DOI: (10.1016/j.athoracsur.2010.11.063) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions